3D spongy graphene-modified screen-printed sensors for the voltammetric determination of the narcotic drug codeine

被引：60
作者：
Mohamed, Mona A. [1 ]
El-Gendy, Dalia M. [2 ]
Ahmed, Nashaat [2 ]
Banks, Craig E. [3 ]
Allam, Nageh K. [2 ]
机构：
[1] Natl Org Drug Control & Res, Pharmaceut Chem Dept, Pyramids Ave,POB 29, Giza, Egypt
[2] Amer Univ Cairo, Sch Sci & Engn, Energy Mat Lab, New Cairo 11835, Egypt
[3] Manchester Metropolitan Univ, Fac Sci & Engn, Chester St, Manchester M1 5GD, Lancs, England
来源：
BIOSENSORS & BIOELECTRONICS | 2018年 / 101卷
关键词：
Green synthesis; Spongy graphene; Screen-printed sensors; Codeine; Adenine; GLASSY-CARBON ELECTRODE; ELECTROCHEMICAL SENSOR; SENSITIVE DETERMINATION; PARACETAMOL; OXIDE; CAFFEINE; ACETAMINOPHEN; NANOTUBES; NANOPARTICLES; TRAMADOL;
D O I：
10.1016/j.bios.2017.10.020
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Adenine-functionalized spongy graphene (FSG) composite, fabricated via a facile and green synthetic method, has been explored as a potential electrocatalyst toward the electroanalytical sensing of codeine phosphate (COD). The synthesized composite is characterized using Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray powder diffraction, UV-vis absorption spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy (HRTEM), and thermogravimetric analysis. The FSG was electrically wired via modification upon screen-printed (macro electrode) sensors, which behave as a hybrid electrode material for the sensitive and selective codeine phosphate (COD) determination in the presence of paracetamol (PAR) and caffeine (CAF). The FSG- modified sensor showed an excellent electrocatalytic response towards the sensing of COD with a wide linear response range of 2.0 x 10(-8)-2.0 x 10(-4) M and a detection limit (LOD) of 5.8 x 10(-9) M, indicating its potential for the sensing of COD in clinical samples and pharmaceutical formulations.
引用
收藏
页码：90 / 95
页数：6
相关论文
共 41 条
  • [11] DISPOSITION AND METABOLISM OF CODEINE AFTER SINGLE AND CHRONIC DOSES IN ONE POOR AND 7 EXTENSIVE METABOLIZERS
    CHEN, ZR
    SOMOGYI, AA
    REYNOLDS, G
    BOCHNER, F
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1991, 31 (04) : 381 - 390
  • [12] An Electrochemical Sensor for the Simultaneous Determination of Paracetamol and Codeine Using a Glassy Carbon Electrode Modified with Nickel Oxide Nanoparticles and Carbon Black
    Deroco, Patricia Batista
    Vicentini, Fernando Campanha
    Fatibello-Filho, Orlando
    [J]. ELECTROANALYSIS, 2015, 27 (09) : 2214 - 2220
  • [13] A One-Step, Solvothermal Reduction Method for Producing Reduced Graphene Oxide Dispersions in Organic Solvents
    Dubin, Sergey
    Gilje, Scott
    Wang, Kan
    Tung, Vincent C.
    Cha, Kitty
    Hall, Anthony S.
    Farrar, Jabari
    Varshneya, Rupal
    Yang, Yang
    Kaner, Richard B.
    [J]. ACS NANO, 2010, 4 (07) : 3845 - 3852
  • [14] Adenine-functionalized Spongy Graphene for Green and High-Performance Supercapacitors
    El-Gendy, Dalia M.
    Ghany, Nabil A. Abdel
    El Sherbini, E. E. Foad
    Allam, Nageh K.
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [15] A new electrochemical sensor for the simultaneous determination of acetaminophen and codeine based on porous silicon/palladium nanostructure
    Ensafi, Ali A.
    Ahmadi, Najmeh
    Rezaei, Behzad
    Abarghoui, Mehdi Mokhtari
    [J]. TALANTA, 2015, 134 : 745 - 753
  • [16] A new voltammetric sensor for electrocatalytic determination of vitamin C in fruit juices and fresh vegetable juice using modified multi-wall carbon nanotubes paste electrode
    Gheibi, Siamak
    Karimi-Maleh, Hassan
    Khalilzadeh, Mohammad A.
    Bagheri, Hasan
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2015, 52 (01): : 276 - 284
  • [17] Simultaneous determination of codeine and caffeine using single-walled carbon nanotubes modified carbon-ceramic electrode
    Habibi, Biuck
    Abazari, Mehri
    Pournaghi-Azar, Mohammad Hossein
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 114 : 89 - 95
  • [18] Comparison of fatal poisonings by prescription opioids
    Hakkinen, Margareeta
    Launiainen, Terhi
    Vuori, Erkki
    Ojanpera, Ilkka
    [J]. FORENSIC SCIENCE INTERNATIONAL, 2012, 222 (1-3) : 327 - 331
  • [19] Graphene Quantum Sheets with Multiband Emission: Unravelling the Molecular Origin of Grapherie Quantum Dots
    Hassanien, Ahmed S.
    Shedeed, Radwa A.
    Allam, Nageh K.
    [J]. JOURNAL OF PHYSICAL CHEMISTRY C, 2016, 120 (38) : 21678 - 21684
  • [20] ICH, 1997, INT C HARM GEN SWITZ, V19, P62
12345