Studies on the performance of selective laser melting porous dental implant by finite element model simulation, fatigue testing and in vivo experiments

被引:20
作者
Wang, Yaling [1 ]
Chen, Xianshuai [2 ,3 ]
Zhang, Chunyu [4 ]
Feng, Wei [5 ]
Zhang, Peng [6 ]
Chen, Yang [7 ]
Huang, Jiaming [5 ]
Luo, Yuanxin [1 ]
Chen, Jianyu [8 ]
机构
[1] Chongqing Univ, State Key Lab Mech Transmiss, Chongqing 400030, Peoples R China
[2] Guangzhou Janus Biotechnol Co Ltd, Guangzhou, Guangdong, Peoples R China
[3] Chinese Univ Hong Kong, Shatin, Hong Kong, Peoples R China
[4] Foshan Angels Biotechnol Co Ltd, Foshan, Peoples R China
[5] Chinese Acad Sci, SIAT, Shenzhen, Peoples R China
[6] Foshan Stomatol Hosp, Foshan, Peoples R China
[7] Shenzhen Second Peoples Hosp, Shenzhen, Peoples R China
[8] Sun Yat Sen Univ, Guanghua Sch Stomatol, Hosp Stomatol, Guangdong Prov Key Lab Stomatol, Guangzhou 510055, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
Porous structure; dental implant; selective laser melting; biomechanical; osseointegration; STEM STIFFNESS; BONE; TITANIUM; SCAFFOLDS; DESIGN; SIZE; FABRICATION; COMPONENTS; GEOMETRY; INGROWTH;
D O I
10.1177/0954411918816114
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Biomaterials have been widely used for stomatological reconstructive surgery in recent years. Many studies have demonstrated that the porous structure of an implant promotes bone ingrowth and its stiffness can be controlled via the design of the porosity. Although some researchers have paid attention to investigating the porous structure for dental implants, the biomechanical properties and osseointegration have not been well studied. In this study, finite element analysis and experiments have been used to evaluate the biomechanical performance and osseointegration of dental implants with porous/solid structures fabricated by selective laser melting using commercially pure titanium (CP-Ti, Grade 2). The implants were tested and the fracture surfaces were observed by scanning electron microscope to investigate the failure mechanisms. To reduce bone resorption, the porosity of dental implant was designed to optimize its stiffness. Finally, animal experiments revealed that bone tissue ingrowth was seen into the porous structure. It is believed that the porous dental implants have great potential in future applications.
引用
收藏
页码:170 / 180
页数:11
相关论文
共 38 条
[1]  
Binon PP, 2000, INT J ORAL MAX IMPL, V15, P76
[2]  
BOBYN JD, 1990, CLIN ORTHOP RELAT R, P196
[3]  
Brunski J B, 1999, Adv Dent Res, V13, P99
[4]   An initial investigation of photocurable three-dimensional lactic acid based scaffolds in a critical-sized cranial defect [J].
Burdick, JA ;
Frankel, D ;
Dernell, WS ;
Anseth, KS .
BIOMATERIALS, 2003, 24 (09) :1613-1620
[5]   Influence of custom-made implant designs on the biomechanical performance for the case of immediate post-extraction placement in the maxillary esthetic zone: a finite element analysis [J].
Chen, Jianyu ;
Zhang, Zhiguang ;
Chen, Xianshuai ;
Zhang, Xiao .
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 2017, 20 (06) :636-644
[6]   DESIGN AND MANUFACTURE OF CUSTOMIZED DENTAL IMPLANTS BY USING REVERSE ENGINEERING AND SELECTIVE LASER MELTING TECHNOLOGY [J].
Chen, Jianyu ;
Zhang, Zhiguang ;
Chen, Xianshuai ;
Zhang, Chunyu ;
Zhang, Gong ;
Xu, Zhewu .
JOURNAL OF PROSTHETIC DENTISTRY, 2014, 112 (05) :1088-+
[7]  
Currey J, 1984, SCIENCE, V227, P629
[8]  
de Wild M, 2013, TISSUE ENG PT A, V19, P2645, DOI [10.1089/ten.tea.2012.0753, 10.1089/ten.TEA.2012.0753]
[9]   Fabrication of biocompatible titanium scaffolds using space holder technique [J].
Dezfuli, S. Naddaf ;
Sadrnezhaad, S. K. ;
Shokrgozar, M. A. ;
Bonakdar, S. .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2012, 23 (10) :2483-2488
[10]  
Eckert Steven E, 2002, J Prosthodont, V11, P194, DOI 10.1053/jpro.2002.127768