Pd-Catalyzed Asymmetric Allylic Etherizations with Oximes by Chiral Alkene-Phosphine Ligands

被引：35

作者：

Cao, Ziping ^{[1
]}

Liu, Zhaoqun ^{[1
]}

Liu, Yilin ^{[1
]}

Du, Haifeng ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 15期

基金：

美国国家科学基金会;

关键词：

DIENE LIGANDS; ENANTIOSELECTIVE SYNTHESIS; STEERING LIGANDS; AMINO-ACIDS; ETHERS; OLEFINS; REARRANGEMENT; SUBSTITUTION; ALDOXIMES; 1,4-ADDITION;

D O I：

10.1021/jo200925q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed asymmetric allylic etherizations with a variety of mimes as nucleophiles utilizing a chiral alkene-phosphine hybrid ligand have been successfully achieved for the first time to afford the optical active oxime ethers in high yields with good to excellent enantioselectivities.

引用

页码：6401 / 6406

页数：6

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