Selective acceleration for deprotection of benzyl ethers with Ti-HMS

被引：29

作者：

Itoh, A

Kodama, T

Maeda, S

Masaki, Y

机构：

[1] Gifu Pharmaceut Univ, Gifu 5028585, Japan

[2] Fukui Univ, Fac Engn, Dept Appl Chem & Biotechnol, Fukui 9100017, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(98)02145-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ti-HMS, a TI-loaded hexagonal mesoporous silica, was found to accelerate deprotection of benzyl ethers under hydrogenolytic conditions with palladium catalyst. Such acid-sensitive functional groups as silyl ether and acetal moieties in the molecule were little affected by Ti-HMS, which possesses Lewis acid sites due to Ti-atom. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：9461 / 9464

页数：4

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