The Multidimensional Nature of Antiviral Innate Immunity

被引:1
|
作者
Harris, Reuben S. [1 ,2 ]
Perrino, Fred W. [3 ]
Shaban, Nadine M. [1 ,2 ]
机构
[1] Univ Minnesota, Ctr Genome Engn, Inst Mol Virol, Dept Biochem Mol Biol & Biophys, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Mason Canc Ctr, Minneapolis, MN 55455 USA
[3] Wake Forest Univ, Bowman Gray Sch Med, Struct Biol Ctr, Dept Biochem, Winston Salem, NC 27157 USA
关键词
VIRUS;
D O I
10.1016/j.chom.2015.03.011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Viruses possess elaborate defensive mechanisms to evade host innate immune responses. In this issue of Cell Host & Microbe, Stavrou et al. (2015) reveal how the murine leukemia virus uses a sugar-protein shield to protect from inevitable destruction by cellular innate immune factors including the APOBEC3 DNA mutating enzyme.
引用
收藏
页码:423 / 425
页数:4
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