Prospective Association of the Portfolio Diet with All-Cause and Cause-Specific Mortality Risk in the Mr. OS and Ms. OS Study

被引:6
|
作者
Lo, Kenneth [1 ,2 ]
Glenn, Andrea J. [3 ,4 ,5 ]
Yeung, Suey [6 ]
Kendall, Cyril W. C. [3 ,4 ,5 ,7 ]
Sievenpiper, John L. [3 ,4 ,5 ,8 ,9 ,10 ]
Jenkins, David J. A. [3 ,4 ,5 ,8 ,9 ,10 ]
Woo, Jean [6 ]
机构
[1] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hung Hom, Kowloon, 11 Yuk Choi Rd, Hong Kong, Peoples R China
[2] Hong Kong Polytech Univ, Res Inst Smart Ageing, Hong Kong, Peoples R China
[3] Univ Toronto, Temerty Fac Med, Dept Nutr Sci, Toronto, ON M5S 1A8, Canada
[4] St Michaels Hosp, Clin Nutr & Risk Factor Modificat Ctr, Toronto, ON M5C 2T2, Canada
[5] St Michaels Hosp, Toronto 3D Knowledge Synth & Clin Trials Unit, Toronto, ON M5C 2T2, Canada
[6] Chinese Univ Hong Kong, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China
[7] Univ Saskatchewan, Coll Pharm & Nutr, Saskatoon, SK S7N 5E5, Canada
[8] Univ Toronto, Temerty Fac Med, Dept Med, Toronto, ON M5S 1A8, Canada
[9] St Michaels Hosp, Li Ka Shing Knowledge Inst, Toronto, ON M5B 1A6, Canada
[10] St Michaels Hosp, Dept Med, Div Endocrinol & Metab, Toronto, ON M5C 2T2, Canada
基金
加拿大健康研究院; 加拿大创新基金会;
关键词
Portfolio Diet; Asian population; mortality; cardiovascular disease; cancer; prospective cohort; CHOLESTEROL-LOWERING FOODS; SERUM-LIPIDS; PHYTOSTEROLS; PATTERNS; OUTCOMES; DISEASE; CANCER; HEALTH;
D O I
10.3390/nu13124360
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The Portfolio Diet has demonstrated its cardiovascular benefit from interventions, but the association between Portfolio Diet adherence and the risk of all-cause and cause-specific mortality has not been examined in Chinese population. The present study has collected Portfolio Diet adherence (assessed by food frequency questionnaire), lifestyle factors and mortality status of 3991 participants in the Mr. Osteoporosis (OS) and Ms. OS Study. Cox regression models were used to examine the association between the Portfolio Diet adherence and mortality risk (all-cause, cardiovascular disease or cancer). The highest quartile of the Portfolio Diet score was associated with a 28% lower risk of all-cause (hazard ratio, HR: 0.72) and cancer (HR: 0.72) mortality, respectively. The association between Portfolio Diet adherence and cardiovascular disease mortality did not reach statistical significance (HR: 0.90, 95% CI = 0.64, 1.26). Among male participants, the highest adherence to the Portfolio Diet was also associated with a lower risk of all-cause (HR: 0.63) and cancer mortality (HR: 0.59), and there was an inverse association between food sources of plant protein and the risk of cardiovascular mortality (HR: 0.50). However, most associations between the Portfolio Diet and mortality were not significant among females. The protection for cancer mortality risk might reach the plateau at the highest adherence to the Portfolio Diet for females. To conclude, greater adherence to the Portfolio Diet was significantly associated with a lower risk of mortality in Hong Kong older adults, and the associations appeared stronger among males.
引用
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页数:13
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