Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease

被引：7

作者：

Pichler, Judith ^{[2
]}

Zilbauer, Matthias ^{[1
]}

Torrente, Franco ^{[1
]}

Heuschkel, Robert ^{[1
]}

Phillips, Alan ^{[3
]}

Salvestrini, Camilla ^{[1
]}

机构：

[1] Addenbrookes Hosp, Dept Paediat Gastroenterol, Cambridge CB2 0QQ, England

[2] Med Univ Vienna, Dept Paediat & Adolescent Med, A-1090 Vienna, Austria

[3] Royal Free Hosp, Ctr Paediat Gastroenterol, London NW3 2QG, England

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2011年 / 17卷 / 14期

关键词：

Coeliac disease; Self-testing kit; Second-degree relatives;

D O I：

10.3748/wjg.v17.i14.1840

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

AIM: To assess feasibility of a finger prick-based kit as method for self-testing of first and second-degree relatives of coeliac disease (CD) patients. METHODS: A total number of 379 subjects were invited to participate in this study, consisting of 197 first-degree and 182 second-degree relatives of CD patients. The self-testing kit (Biocard (TM)) was sent out with included instructions for use. Completed tests were sent back to the study coordinator for assessment. RESULTS: One hundred and ninety-six invited relatives carried out the Biocard (TM) test at home. Amongst these, 70% were children. In 97% of the cases the test was performed correctly. Three tests revealed a positive result, all of which were later confirmed by serology and histology as coeliac disease. CONCLUSION: Our study indicates that Biocard (TM) test is a reliable, easy to use and well-accepted tool for home testing of first- and second-degree relatives of CD patients. (C) 2011 Baishideng. All rights reserved.

引用

页码：1840 / 1843

页数：4

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