VIRAL COINFECTION IN CHILDREN LESS THAN FIVE YEARS OLD WITH INVASIVE PNEUMOCOCCAL DISEASE

被引：33

作者：

Launes, Cristian ^{[1
]}

de-Sevilla, Mariona-Fernandez ^{[1
]}

Selva, Laura ^{[2
]}

Garcia-Garcia, Juan-Jose ^{[1
]}

Pallares, Roman ^{[3
]}

Munoz-Almagro, Carmen ^{[2
]}

机构：

[1] Univ Barcelona, Dept Pediat, Infect Dis Unit, Hosp St Joan de Deu, Barcelona, Spain

[2] Univ Barcelona, Dept Mol Microbiol, Hosp St Joan de Deu, Barcelona, Spain

[3] Univ Barcelona, Bellvitge Hosp, Infect Dis Serv, Barcelona, Spain

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2012年 / 31卷 / 06期

关键词：

Streptococcus pneumoniae; serotypes; respiratory virus; real-time polymerase chain reaction; pneumococcal disease; STREPTOCOCCUS-PNEUMONIAE; ASSOCIATION; SEROTYPES; CARRIAGE;

D O I：

10.1097/INF.0b013e31824f25b0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Seventy-one patients <5 years of age who were hospitalized with invasive pneumococcal disease were studied in the period between August 2008 and December 2009. The purpose was to determine the proportion of episodes that were coinfected with respiratory virus. Viral coinfection was common (44/71; 62%), with rhinovirus and influenza virus being the most frequently detected. Highly invasive serotypes (1, 5, 7F, 14, 19A) were found in 31 of 71 patients, of whom 15 had viral coinfection (15/31; 48%). Viral detection occurred significantly more often in those episodes caused by nonhighly invasive serotypes (29/40; 72%), suggesting that a viral synergism could help those serotypes to make invasiveness more likely.

引用

页码：650 / 653

页数：5

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