Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

被引:24
作者
Murer, P [1 ]
Lewandowski, K [1 ]
Svec, F [1 ]
Fréchet, JMJ [1 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
关键词
D O I
10.1039/a806397d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.
引用
收藏
页码:2559 / 2560
页数:2
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