Branching out with DNA helicases

被引：4

作者：

Yusufzai, Timur ^{[1
,2
]}

Kadonaga, James T. ^{[3
]}

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Dept Radiat Oncol, Boston, MA 02215 USA

[3] Univ Calif San Diego, Mol Biol Sect, La Jolla, CA 92093 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2011年 / 21卷 / 02期

基金：

美国国家卫生研究院;

关键词：

SIMPLE REPETITIVE SEQUENCES; STALLED REPLICATION FORKS; COMPLEMENTATION GROUP-M; HOLLIDAY JUNCTIONS; ANNEALING HELICASE; SYNDROME PROTEINS; STRANDED-DNA; REPAIR; RECG; FANCM;

D O I：

10.1016/j.gde.2011.01.019

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The proper resolution of branched DNA molecules, which arise during processes such as DNA replication, DNA repair, and transcription, is critical for the maintenance of the genome. Disruption of this process can lead to genome instability and cancer progression. In this review, we describe recent progress on several interesting and biologically important enzymes that act upon different types of branched DNA substrates.

引用

页码：214 / 218

页数：5

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