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LYME NEUROBORRELIOSIS
被引:0
|作者:
Milovanovic, A.
[1
]
Milovanovic, J.
Obrenovic, Sonja
[2
]
Milovanovic, Andela
[3
]
Simonovic, P.
[4
]
Cemerikic, D.
Tacevic, Z.
Petronic, Ivana
Grajic, M.
Kekus, Divna
[5
]
Popevic, M.
机构:
[1] Shool Med, Inst Occupat Hlth Serbia, Belgrade 11000, Serbia
[2] Univ Belgrade, Fac Vet Med, Belgrade, Serbia
[3] Clin Ctr Serbia, Belgrade, Serbia
[4] Minist Hlth, Belgrade, Serbia
[5] High Med Shool, Zemun, Serbia
来源:
关键词:
neuroborreliosis;
ELISA;
occupational capacity;
LINKED-IMMUNOSORBENT-ASSAY;
BURGDORFERI-SENSU-LATO;
ACRODERMATITIS CHRONICA ATROPHICANS;
BORRELIA-BURGDORFERI;
INDIRECT IMMUNOFLUORESCENCE;
CLINICAL-MANIFESTATIONS;
CEREBROSPINAL-FLUID;
DISEASE;
SERODIAGNOSIS;
ANTIBODIES;
D O I:
10.2298/AVB1101089M
中图分类号:
S85 [动物医学(兽医学)];
学科分类号:
0906 ;
摘要:
Lyme borreliosis (LB) is a multisystemic zoonotic disease which in humans can involve the skin, joints, heart and/or nervous system. In this study a total of 11 patients with clinical manifestations have been assessed at the Institute for Occupational Health. Evaluation of the patients was done in order to determine their working capability and further professional orientation. Patients were of different gender, age, education and profession. They fulfilled at least two of the three criteria: tick infestation data (epidemiological criteria), central and/or peripheral neurological symptoms (clinical criteria) and a positive serological finding. Diagnosis was done upon classical clinical criteria: electro-myeloneurography (EMNG) analysis, neurological impairments, electroencephalography (EEG), computer tomography (CT) and/or magnetic resonance imaging (MRI). IgM and IgG antibodies against B. burgdorferi were determined by commercial ELISA kits. IgM antibodies were recorded in the serum of 4 (44.4%) and IgG in 6 (66.7%) patients. Electro-myeloneurography findings of the upper and lower limbs were positive in 5 (83.3%), electroencephalography in 4 (66.6%) of the 6 observed patients and CT was positive in 4 (36.4%) of the 5 observed patients. The study has established that in patients with neuroborreliosis (NB) the capability to carry out intellectual tasks, as well as responsible duties is impaired due to poor memory. Patients suffering from peripheral neuropathies are not fit to withstand longterm walks, weight lifting and carrying or any other form of physical stress.
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页码:89 / 98
页数:10
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