Acute Exacerbation of Idiopathic Pulmonary Fibrosis

被引:30
作者
Kim, Dong Soon [1 ]
机构
[1] Univ Ulsan, Asan Med Ctr, Dept Pulm & Crit Care Med, Seoul, South Korea
关键词
Idiopathic pulmonary fibrosis; Acute exacerbation; Incidence; Risk factors; PLACEBO-CONTROLLED TRIAL; INTERSTITIAL PNEUMONIA; LUNG-DISEASE; CONSECUTIVE PATIENTS; ALPHA-DEFENSINS; CLINICAL-COURSE; CYCLOSPORINE-A; RISK-FACTORS; PIRFENIDONE; PROFILES;
D O I
10.1016/j.ccm.2012.01.001
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive and ultimately fatal disease, the clinical course of which in individual patients is highly variable. Sudden deterioration of a patient's respiratory condition during a stable course is not uncommon. Many cases of uncertain etiology have been called acute exacerbation (AEx) of IPF, under the assumption of sudden acceleration of the underlying disease process. In recent years, several studies have reported the clinical significance of AEx-IPF. In 2007 Collard and colleagues created a Consensus Perspective, which proposed consensus definition and standard diagnostic criteria. This review primarily discusses studies performed after this Consensus Perspective.
引用
收藏
页码:59 / +
页数:11
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