In vivo assessment of emphysema in mice by high resolution X-ray microtomography

被引：41
作者：
Postnov, AA
Meurrens, K
Weiler, H
Van Dyck, D
Hu, X
Terpstra, P
De Clerck, NM
机构：
[1] Univ Antwerp, Dept Biomed Sci, B-2610 Antwerp, Belgium
[2] Univ Antwerp, Dept Phys, B-2610 Antwerp, Belgium
[3] PHILIP MORRIS Res Labs, B-3001 Louvain, Belgium
[4] PHILIP MORRIS Res Labs, D-51149 Cologne, Germany
来源：
JOURNAL OF MICROSCOPY | 2005年 / 220卷
关键词：
3D rendering; emphysema; in vivo scanning; X-ray microtomography;
D O I：
10.1111/j.1365-2818.2005.01510.x
中图分类号：
TH742 [显微镜];
学科分类号：
摘要：
High resolution X-ray microtomography (micro-CT) was used for the detection of emphysema in live mice. Emphysema was induced in C57BL/6 J mice by intratracheal instillation of different amounts of porcine pancreatic elastase. This emphysema could be clearly detected by micro-CT seven weeks post-treatment: analysis of the whole data set of virtual cross-sections showed the presence of a dose-dependent level of emphysema.
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收藏
页码：70 / 75
页数：6
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