Remission of a B cell CLL-associated membranoproliferative glomerulonephritis type I with rituximab and bendamustine

被引：0

作者：

Bartel, C. ^{[1
]}

Obermueller, N. ^{[1
]}

Rummel, M. J. ^{[2
]}

Geiger, H. ^{[1
]}

Hauser, I. A. ^{[1
]}

机构：

[1] Univ Hosp Frankfurt, Med Clin 3, Dept Nephrol, D-60590 Frankfurt, Germany

[2] Univ Hosp Giessen, Dept Hematol & Oncol, Giessen, Germany

来源：

CLINICAL NEPHROLOGY | 2008年 / 69卷 / 04期

关键词：

rituximab therapy; membranoproliferative glomerulonephritis; lymphoma; nephrotic syndrome;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In a 56-year-old white male patient, a membranoproliferative glomerulonephritis Type I was diagnosed after a 12-month history of low grade B cell lyrnphoma (Binet A). HIV, Hepatitis B and C serology were negative. Due to an impairment of renal function despite chemotherapy with COP, an in,imunocheiriotherapy consisting of rituximab (6 cycles) and bendamustine (4 cycles) was given. This therapeutic approach caused a complete remission of the nephrotic syndrome. Renal function and arterial hypertension improved markedly. In addition, urinary sediment became normal and proteinuria disappeared completely.

引用

页码：285 / 289

页数：5

共 18 条

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