Chaperone-usher pathways: diversity and pilus assembly mechanism

被引:102
作者
Busch, Andreas
Waksman, Gabriel [1 ]
机构
[1] UCL, ISMB, London WC1E 7HX, England
基金
英国惠康基金;
关键词
chaperone-usher; pilus biogenesis; host-pathogen interactions; DONOR-STRAND EXCHANGE; BACTERIAL OUTER-MEMBRANE; SUBUNIT COMPLEX RECOGNITION; PSEUDOMONAS-AERUGINOSA; CRYSTAL-STRUCTURE; ESCHERICHIA-COLI; STRUCTURAL BASIS; FIMBRIAL OPERON; YERSINIA-PESTIS; GENE CLUSTERS;
D O I
10.1098/rstb.2011.0206
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Up to eight different types of secretion systems, and several more subtypes, have been described in Gram-negative bacteria. Here, we focus on the diversity and assembly mechanism of one of the best-studied secretion systems, the widespread chaperone-usher pathway known to assemble and secrete adhesive surface structures, called pili or fimbriae, which play essential roles in targeting bacterial pathogens to the host.
引用
收藏
页码:1112 / 1122
页数:11
相关论文
共 61 条
  • [1] BIOGENESIS OF ESCHERICHIA-COLI PAP PILI - PAPH, A MINOR PILIN SUBUNIT INVOLVED IN CELL ANCHORING AND LENGTH MODULATION
    BAGA, M
    NORGREN, M
    NORMARK, S
    [J]. CELL, 1987, 49 (02) : 241 - 251
  • [2] Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly
    Barnhart, MM
    Sauer, FG
    Pinkner, JS
    Hultgren, SJ
    [J]. JOURNAL OF BACTERIOLOGY, 2003, 185 (09) : 2723 - 2730
  • [3] Baumler AJ, 1997, J BACTERIOL, V179, P317
  • [4] BAUMLER AJ, 1995, J BACTERIOL, V177, P2087
  • [5] The lpf fimbrial operon mediates adhesion of Salmonella typhimurium to murine Peyer's patches
    Baumler, AJ
    Tsolis, RM
    Heffron, F
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (01) : 279 - 283
  • [6] STRUCTURE FUNCTION SYNTHESIS AND GENETIC CONTROL OF BACTERIAL PILI AND A MOLECULAR MODEL FOR DNA AND RNA TRANSPORT IN GRAM NEGATIVE BACTERIA
    BRINTON, CC
    [J]. TRANSACTIONS OF THE NEW YORK ACADEMY OF SCIENCES, 1965, 27 (08): : 1003 - &
  • [7] NON-FLAGELLAR APPENDAGES OF BACTERIA
    BRINTON, CC
    [J]. NATURE, 1959, 183 (4664) : 782 - 786
  • [8] Structural and Functional Characterization of Pseudomonas aeruginosa CupB Chaperones
    Cai, Xun
    Wang, Rui
    Filloux, Alain
    Waksman, Gabriel
    Meng, Guoyu
    [J]. PLOS ONE, 2011, 6 (01):
  • [9] Evidence for a novel domain of bacterial outer membrane ushers
    Capitani, Guido
    Eidam, Oliv
    Gruetter, Markus G.
    [J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2006, 65 (04) : 816 - 823
  • [10] X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli
    Choudhury, D
    Thompson, A
    Stojanoff, V
    Langermann, S
    Pinkner, J
    Hultgren, SJ
    Knight, SD
    [J]. SCIENCE, 1999, 285 (5430) : 1061 - 1066