The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS

被引：2
|
作者：
Hofman, Isabel Juliana F. [1 ]
Mortera-Blanco, Teresa [1 ]
Moura, Pedro Luis [1 ]
Vestlund, Johanna [1 ]
Larsson, Sigita Venckute [1 ]
Elvarsdottir, Edda M. [1 ]
Walldin, Gunilla [1 ]
Tobiasson, Magnus [1 ,2 ]
Sander, Birgitta [3 ]
Dimitriou, Marios [1 ,4 ]
Jacobsen, Sten-Eirik W. [1 ,4 ]
Woll, Petter S. [1 ,4 ]
Jadersten, Martin [2 ]
Hellstrom-Lindberg, Eva [1 ,2 ]
机构：
[1] Karolinska Inst, Dept Med Huddinge, Ctr Hematol & Regenerat Med, Huddinge, Sweden
[2] Karolinska Univ Hosp, Dept Hematol, Huddinge, Sweden
[3] Karolinska Univ Hosp, Div Pathol, Dept Lab Med, Huddinge, Sweden
[4] Karolinska Inst, Dept Cell & Mol Biol, Stockholm, Sweden
来源：
BLOOD ADVANCES | 2022年 / 6卷 / 16期
关键词：
ERYTHROPOIETIN-STIMULATING AGENTS; MYELODYSPLASTIC SYNDROMES; MUTATIONS;
D O I：
10.1182/bloodadvances.2022007858
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：4705 / 4709
页数：5
相关论文
共 50 条
  • [1] SF3B1 AND MDS-RS: THE BIOLOGICAL PERSPECTIVE
    Fontenay, M.
    LEUKEMIA RESEARCH, 2023, 128
  • [2] TARGETING THE DEFECTIVE COA PATHWAY TO IMPROVE ERYTHROPOIESIS IN SF3B1-MUTANT MDS-RS PATIENTS
    Philippe, C.
    Mian, S.
    Maniati, E.
    Protopapa, P.
    Bergot, T.
    Piganeau, M.
    Nemkov, T.
    Di Bella, D.
    Morales, V.
    Finch, A.
    D'Alessandro, A.
    Bianchi, K.
    Wang, J.
    Gallipoli, P.
    Kordasti, S.
    Kubasch, A. S.
    Cross, M.
    Platzbecker, U.
    Wiseman, D.
    Bonnet, D.
    Bernard, D.
    Gribben, J.
    Rouault-Pierre, K.
    LEUKEMIA RESEARCH, 2023, 128
  • [3] SF3B1 MUTATIONS IN MDS-RS ARISE IN MULTIPOTENT HEMOPOETIC STEM CELLS
    Mortera-Blanco, T.
    Dimitriou, M.
    Woll, P. S.
    Elvarsdottir, E.
    Karimi, M.
    Conte, S.
    Jansson, M.
    Douagi, I.
    Papaemmanuil, E.
    Jacobsen, S. E.
    Hellstrom-Lindberg, E.
    HAEMATOLOGICA, 2016, 101 : 159 - 159
  • [4] Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs
    Asimomitis, Georgios
    G. Deslaurnes, Andre
    Kotini, Andriana G.
    Bernard, Elsa
    Esposito, Davide
    Olszewska, Malgorzata
    Spyrou, Nikolaos
    Ossa, Juan Arango
    Mortera-Blanco, Teresa
    Koche, Richard
    Malcovati, Luca
    Ogawa, Seishi
    Cazzola, Mario
    Aaronson, Stuart A.
    Hellstro-Lindberg, Eva
    Papaemmanuil, Elli
    Nannya, Yasuhito
    Papapetrou, Eirini P.
    BLOOD ADVANCES, 2022, 6 (10) : 2992 - 3005
  • [5] Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells
    Vivet-Noguer, Raquel
    Tarin, Malcy
    Canbezdi, Christine
    Dayot, Stephane
    Silva, Lisseth
    Houy, Alexandre
    Martineau, Sylvain
    Mieulet, Virginie
    Gentric, Geraldine
    Loew, Damarys
    Lombard, Berangere
    Nemati, Fariba
    Richon, Sophie
    Guyonnet, Lea
    Servois, Vincent
    Vagner, Stephan
    Stern, Marc-Henri
    Roman-Roman, Sergio
    Alsafadi, Samar
    CANCERS, 2022, 14 (09)
  • [6] The Impact of Spliceosome Inhibition in SF3B1-Mutated Uveal Melanoma
    Nguyen, Josephine Q. N.
    Drabarek, Wojtek
    Leeflang, Aisha M. C. H. J.
    Brands, Tom
    van den Bosch, Thierry P. P.
    Verdijk, Robert M.
    van de Werken, Harmen J. G.
    van Riet, Job
    Paridaens, Dion
    de Klein, Annelies
    Brosens, Erwin
    Kilic, Emine
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (12)
  • [7] Long-Term Clonal Inversion in an MDS-RS Case with Dual SF3B1 Mutations
    Moura, Pedro Luis
    Hofman, Isabel Juliana F.
    Nannya, Yasuhito
    Aliouat, Affaf
    Mortera-Blanco, Teresa
    Yoshizato, Tetsuichi
    Saiki, Ryunosuke
    Nakagawa, Masahiro Marshall
    Bjorklund, Ann-Charlotte
    Walldin, Gunilla
    Barbosa, Indira
    Jansson, Monika
    Grasso, Francesca
    Creignou, Maria
    Elvarsdottir, Edda Maria
    Woll, Petter S.
    Jacobsen, Sten Eirik Waelgaard
    Ogawa, Seishi
    Hellstrom-Lindberg, Eva
    BLOOD, 2022, 140 : 6898 - 6899
  • [8] Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms
    Boiocchi, Leonardo
    Hasserjian, Robert P.
    Pozdnyakova, Olga
    Wong, Waihay J.
    Lennerz, Jochen K.
    Le, Long Phi
    Dias-Santagata, Dora
    Iafrate, Anthony J.
    Hobbs, Gabriela S.
    Nardi, Valentina
    HUMAN PATHOLOGY, 2019, 86 : 1 - 11
  • [9] Upregulation of ZEB1-Derived Circular RNAs Is Associated with SF3B1-Mutated Myelodysplastic Neoplasms
    Trsova, Iva
    Belickova, Monika
    Hrustincova, Andrea
    Kaisrlikova, Monika
    Lenertova, Zuzana
    Kundrat, David
    Krejcik, Zdenek
    Vesela, Jitka
    Klema, Jiri
    Rysavy, Petr
    Cermak, Jaroslav
    Merkerova, Michaela Dostalova
    BLOOD, 2022, 140 : 4005 - 4006
  • [10] SF3B1-Mutant Myelodysplastic Syndrome with Ringed Sideroblasts (MDS-RS) at the Single-Cell Level
    Kanagal-Shamanna, Rashmi
    Adema, Vera
    Ma, Feiyang
    Santoni, Andrea
    Yang, Hui
    Ganan-Gomez, Irene
    Thongon, Natthakan
    Montalban-Bravo, Guillermo
    Pellegrini, Matteo
    Bueso-Ramos, Carlos E.
    Garcia-Manero, Guillermo
    Colla, Simona
    BLOOD, 2020, 136
12345