Phosphorylthioacetamides in the synthesis of annulated quinoxalines

被引：1

作者：

Aleksanyan, D. V. ^{[1
]}

Kozlov, V. A. ^{[1
]}

Odinets, I. L. ^{[1
]}

Petrovskii, P. V. ^{[1
]}

Mastryukova, T. A. ^{[1
]}

机构：

[1] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2007年 / 56卷 / 05期

基金：

俄罗斯基础研究基金会;

关键词：

phosphorylthioacetamides; 2,3-dichloroquinoxaline; N-methylquinoxalinium iodide; annulation; 1,3,3a,4,9,9a-hexahydro-2H-pyrrolo[2,3-b]quinoxaline-2-thiones;

D O I：

10.1007/s11172-007-0157-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diethoxyphosphorylthioacetamide in the reaction with 2,3-dichloroquinoxaline acted as a thionating reagent, giving diethoxyphosphorylacetonitrile and 2-chloro-3-[(3-chloro-2-quinoxalinyl)thio]quinoxaline. Reactions of phosphorylthioacetamides with N-methylquinoxalinium iodide in alcohol media in the presence of a base proceeded stereoselectively to afford cis-3-phosphoryl-1,3,3a,4,9,9a-hexahydro-2H-pyrrolo[2,3-b]quinoxaline-2-thiones.

引用

页码：1049 / 1052

页数：4

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