HaploPainter:: a tool for drawing pedigrees with complex haplotypes

被引：232
作者：
Thiele, H [1 ]
Nürnberg, P
机构：
[1] Max Delbruck Ctr Mol Med, Gene Mapping Ctr, Berlin, Germany
[2] Charite Univ Med Berlin, Inst Med Genet, Berlin, Germany
[3] Univ Cologne, Cologne Ctr Genom, D-5000 Cologne, Germany
来源：
BIOINFORMATICS | 2005年 / 21卷 / 08期
关键词：
D O I：
10.1093/bioinformatics/bth488
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
HaploPainter is a user-friendly pedigree-drawing application with special features for easy visualization of complex haplotype information. It has been developed to facilitate gene mapping in Mendelian diseases in terms of fast and reliable definition of the smallest critical interval harbouring the underlying gene defect. HaploPainter is written in Perl and may be used for visualization of haplotypes calculated by any of the common linkage programs. With special features like haplotype compression or the ability of marker section cut-out it particularly addresses the requirements for viewing large haplotypes as obtained by using for genome scans high-density marker panels of many thousands of single nucleotide polymorphisms (SNPs).
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收藏
页码：1730 / 1732
页数：3
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