Spatial and seasonal heterogeneity of atmospheric particles induced reactive oxygen species in urban areas and the role of water-soluble metals

被引：29

作者：

Gali, Nirmal Kumar ^{[1
]}

Yang, Fenhuan ^{[1
]}

Jiang, Sabrina Yanan ^{[1
]}

Chan, Ka Lok ^{[1
]}

Sun, Li ^{[1
]}

Ho, Kin-fai ^{[2
]}

Ning, Zhi ^{[1
]}

机构：

[1] City Univ Hong Kong, Sch Energy & Environm, Hong Kong, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Jockey Club, Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China

来源：

ENVIRONMENTAL POLLUTION | 2015年 / 198卷

关键词：

Reactive oxygen species; PM2.5; Coarse PM; Urban aerosol; Water-soluble metals; PARTICULATE MATTER PM2.5; OXIDATIVE STRESS; CHEMICAL CHARACTERISTICS; EPITHELIAL-CELLS; AIR-POLLUTANTS; PM10; AEROSOLS; IN-VIVO; GENERATION; FINE; COARSE;

D O I：

10.1016/j.envpol.2015.01.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Adverse health effects are associated with exposure to atmospheric particulate matter (PM), which carry various chemical constituents and induce both exogenous and endogenous oxidative stress. This study investigated the spatial and seasonal variability of PM-induced ROS at four sites with different characteristics in Hong Kong. Cytotoxicity, exogenous and endogenous ROS was determined on a dose and time dependent analysis. Large spatial variation of ROS was observed with fine PM at urban site showing highest ROS levels while coarse PM at traffic site ranks the top. No consistent seasonal difference was observed for ROS levels among all sites. The highly heterogeneous distribution of PM-induced ROS demonstrates the differential capability of PM to produce oxidative stress, and the need to use appropriate metrics as surrogates of exposure instead of PM mass in epidemiologic studies. Several transition metals were found associated with ROS by different degree illustrating the complexity of mechanisms involved. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：86 / 96

页数：11

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