Innate and adaptive immune responses to Listeria monocytogenes:: a short overview

被引：130
作者：
Zenewicz, Lauren A.
Shen, Hao [1 ]
机构：
[1] Univ Penn, Sch Med, Dept Microbiol, Philadelphia, PA 19104 USA
[2] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
来源：
MICROBES AND INFECTION | 2007年 / 9卷 / 10期
关键词：
Listeria monocytogenes; immunity; infection;
D O I：
10.1016/j.micinf.2007.05.008
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model pathogen for elucidating important mechanisms of the immune response. Infection of mice with a sub-lethal dose of bacteria generates highly reproducible innate and adaptive immune responses, resulting in clearance of the bacteria and resistance to subsequent L. monocytogenes infection. Both the innate and adaptive immune systems are crucial to the recognition and elimination of this pathogen from the host. (C) 2007 Elsevier Masson SAS. All rights reserved.
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收藏
页码：1208 / 1215
页数：8
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