Animal models of Helicobacter pylori infection and disease

被引：51

作者：

O'Rourke, JL ^{[1
]}

Lee, A ^{[1
]}

机构：

[1] Univ New S Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 08期

关键词：

helicobacter pylori; gastric disease; animal models;

D O I：

10.1016/S1286-4579(03)00123-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The acceptance of Helicobacter pylori as a major human pathogen has necessitated the development of animal models to help elucidate the pathogenic mechanisms of this bacterium and aid in the development of improved strategies for the treatment of gastric disease. Appropriate models, utilising a range of animal species, have been developed to examine factors such as the influence of host responses and bacterial factors in disease development and the success of new therapeutic regimens, including vaccination, to cure infection. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：741 / 748

页数：8

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