Domain swapping and retroviral assembly

被引：18

作者：

Kingston, RL ^{[1
]}

Vogt, VM

机构：

[1] Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA

[2] Cornell Univ, Dept Mol Biol & Genet, Ithaca, NY 14853 USA

来源：

MOLECULAR CELL | 2005年 / 17卷 / 02期

关键词：

D O I：

10.1016/j.molcel.2005.01.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ivanov et al. (2005) recently reported the structure of a mammalian SCAN domain. The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain-swapped dimer in solution. The authors propose a similar domain-swapping event facilitates HIV-1 assembly, providing a new model for protein-protein interactions underlying viral particle formation.

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收藏

页码：166 / 167

页数：2

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