Cytoskeletal mechanisms of axon outgrowth and pathfinding

被引：26
作者：
Brandt, R [1 ]
机构：
[1] Heidelberg Univ, Dept Neurobiol, D-69120 Heidelberg, Germany
来源：
CELL AND TISSUE RESEARCH | 1998年 / 292卷 / 02期
关键词：
microtubules; microfilaments; neurofilaments; neuronal development;
D O I：
10.1007/s004410051049
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The use of modern techniques involving gene transfer and functional knock-out strategies has lead to new concepts of the way in which cytoskeletal elements interact to produce the unique morphologies of neurons. This review presents these concepts and discusses their implications for neuronal development, especially with respect to the role of microtubules, microfilaments, and neurofilaments.
引用
收藏
页码：181 / 189
页数：9
相关论文
共 98 条
[1]   OVEREXPRESSION OF THE NEURAL GROWTH-ASSOCIATED PROTEIN GAP-43 INDUCES NERVE SPROUTING IN THE ADULT NERVOUS-SYSTEM OF TRANSGENIC MICE [J].
AIGNER, L ;
ARBER, S ;
KAPFHAMMER, JP ;
LAUX, T ;
SCHNEIDER, C ;
BOTTERI, F ;
BRENNER, HR ;
CARONI, P .
CELL, 1995, 83 (02) :269-278
[2]   PROTEIN KINASE-C PHOSPHORYLATES A 47-MR PROTEIN (F1) DIRECTLY RELATED TO SYNAPTIC PLASTICITY [J].
AKERS, RF ;
ROUTTENBERG, A .
BRAIN RESEARCH, 1985, 334 (01) :147-151
[3]   PHOSPHORYLATION OF B-50 PROTEIN BY CALCIUM-ACTIVATED, PHOSPHOLIPID-DEPENDENT PROTEIN-KINASE AND B-50 PROTEIN-KINASE [J].
ALOYO, VJ ;
ZWIERS, H ;
GISPEN, WH .
JOURNAL OF NEUROCHEMISTRY, 1983, 41 (03) :649-653
[4]   PROCESSES INDUCED BY TAU EXPRESSION IN SF9-CELLS HAVE AN AXON-LIKE MICROTUBULE ORGANIZATION [J].
BAAS, PW ;
PIENKOWSKI, TP ;
KOSIK, KS .
JOURNAL OF CELL BIOLOGY, 1991, 115 (05) :1333-1344
[5]   CHANGES IN MICROTUBULE POLARITY ORIENTATION DURING THE DEVELOPMENT OF HIPPOCAMPAL-NEURONS IN CULTURE [J].
BAAS, PW ;
BLACK, MM ;
BANKER, GA .
JOURNAL OF CELL BIOLOGY, 1989, 109 (06) :3085-3094
[6]   POLARITY ORIENTATION OF MICROTUBULES IN HIPPOCAMPAL-NEURONS - UNIFORMITY IN THE AXON AND NONUNIFORMITY IN THE DENDRITE [J].
BAAS, PW ;
DEITCH, JS ;
BLACK, MM ;
BANKER, GA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (21) :8335-8339
[7]   CHROMOPHORE-ASSISTED LASER INACTIVATION OF CELLULAR PROTEINS [J].
BEERMANN, AEL ;
JAY, DG .
METHODS IN CELL BIOLOGY, VOL 44, 1994, 44 :715-732
[8]   Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules [J].
Belmont, LD ;
Mitchison, TJ .
CELL, 1996, 84 (04) :623-631
[9]   GAP-43: An intrinsic determinant of neuronal development and plasticity [J].
Benowitz, LI ;
Routtenberg, A .
TRENDS IN NEUROSCIENCES, 1997, 20 (02) :84-91
[10]  
BINDER LI, 1985, J CELL BIOL, V101, P1371, DOI 10.1083/jcb.101.4.1371
12345678910