Antiviral Potential of Lactic Acid Bacteria and Their Bacteriocins

被引:159
作者
Al Kassaa, I. [1 ,2 ]
Hober, D. [3 ]
Hamze, M. [2 ]
Chihib, N. E. [1 ]
Drider, D. [1 ]
机构
[1] Univ Lille 1, Inst Charles Viollette, Cite Sci, F-59655 Villeneuve Dascq, France
[2] EDST Univ Libanaise Tripoli, AZM Ctr Biotechnol, Lab Microbiol Sante & Environm, Tripoli, Lebanon
[3] Univ Lille 2, Fac Med, CHRU Lille, Lab Virol EA3610, F-59120 Loos Lez Lille, France
关键词
Probiotics; Lactic acid bacteria; Bacteriocins; Antiviral agents; HERPES-SIMPLEX-VIRUS; LACTOBACILLUS-RHAMNOSUS; DOUBLE-BLIND; INFANT MICE; IN-VITRO; PROBIOTICS; CHILDREN; DURATION; DIARRHEA; TYPE-1;
D O I
10.1007/s12602-014-9162-6
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Emerging resistance to antiviral agents is a growing public health concern worldwide as it was reported for respiratory, sexually transmitted and enteric viruses. Therefore, there is a growing demand for new, unconventional antiviral agents which may serve as an alternative to the currently used drugs. Meanwhile, published literature continues shedding the light on the potency of lactic acid bacteria (LAB) and their bacteriocins as antiviral agents. Health-promoting LAB probiotics may exert their antiviral activity by (1) direct probiotic-virus interaction; (2) production of antiviral inhibitory metabolites; and/or (3) via stimulation of the immune system. The aim of this review was to highlight the antiviral activity of LAB and substances they produce with antiviral activity.
引用
收藏
页码:177 / 185
页数:9
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