A facile one-pot sonochemical synthesis of surface-coated mannosyl protein microspheres for detection and killing of bacteria

被引：19

作者：

Skirtenko, Natalia ^{[1
,2
]}

Richman, Michal ^{[1
]}

Nitzan, Yeshayahu ^{[3
]}

Gedanken, Aharon ^{[1
,2
]}

Rahimipour, Shai ^{[1
]}

机构：

[1] Bar Ilan Univ, Dept Chem, IL-52900 Ramat Gan, Israel

[2] Bar Ilan Univ, Inst Nanotechnol & Adv Mat, IL-52900 Ramat Gan, Israel

[3] Bar Ilan Univ, Fac Life Sci, IL-52900 Ramat Gan, Israel

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 45期

关键词：

ALBUMIN MICROSPHERES; ALBUNEX(R); BINDING;

D O I：

10.1039/c1cc13518j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a remarkably facile one-pot sonochemical approach to prepare protein microspheres whose shells are covalently decorated with a mannosyl derivative to target Escherichia coli (E. coli), while their cores are encapsulated with tetracycline. Conjugated microspheres induced the agglutination of E. coli and increased the anti-bacterial activity of the encapsulated tetracycline by five fold.

引用

页码：12277 / 12279

页数：3

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