Recent Advances in Organic Synthesis of 3-Amino- or 4-Aminocoumarins

被引：1
作者：
Chen, Zhiwei [1 ,2 ]
Zeng, Piaopiao [1 ,2 ]
Zhang, Shuo [1 ,2 ]
Sun, Jie [1 ,2 ]
机构：
[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China
[2] Zhejiang Univ Technol, Inst Drug Synth, Hangzhou 310014, Peoples R China
来源：
MINI-REVIEWS IN ORGANIC CHEMISTRY | 2022年 / 19卷 / 04期
关键词：
4-aminocoumarin; 3-aminocoumarin; heterocycles; multicomponent; review synthesis; organic synthesis; SOLVENT-FREE SYNTHESIS; ONE-POT SYNTHESIS; COUMARIN DERIVATIVES; BIOLOGICAL EVALUATION; MULTICOMPONENT SYNTHESIS; FLUORESCENCE CHARACTERISTICS; 3-COMPONENT APPROACH; ANTIFUNGAL ACTIVITY; EFFICIENT SYNTHESIS; MONOAMINE-OXIDASE;
D O I：
10.2174/1570193X18666211001124004
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Coumarin is a privileged scaffold that contains the unique 2H-chromen-2-one motif, and its derivatives are widely distributed in nature, especially in plants. In recent years, due to their diverse pharmacological activities and remarkable photochemical properties, they have attracted significant attention from scientists, which has also prompted the research on the synthesis approaches and the availability of substrates for these compounds. This article is a brief description of the methods for the synthesis of various coumarin derivatives via two-or multi-component reactions involving 3-amino or 4-aminocoumarin reported during 2015-2021. This review may help expand the development of various analogues with coumarin as the basic unit.
引用
收藏
页码：451 / 479
页数：29
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