The mouse Gene Expression Database (GXD): updates and enhancements

被引：50

作者：

Hill, DP ^{[1
]}

Begley, DA ^{[1
]}

Finger, JH ^{[1
]}

Hayamizu, TF ^{[1
]}

McCright, IJ ^{[1
]}

Smith, CM ^{[1
]}

Beal, JS ^{[1
]}

Corbani, LE ^{[1
]}

Blake, JA ^{[1
]}

Eppig, JT ^{[1
]}

Kadin, JA ^{[1
]}

Richardson, JE ^{[1
]}

Ringwald, M ^{[1
]}

机构：

[1] Jackson Lab, Bar Harbor, ME 04609 USA

来源：

NUCLEIC ACIDS RESEARCH | 2004年 / 32卷

关键词：

D O I：

10.1093/nar/gkh069

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Gene Expression Database (GXD) is a community resource for gene expression information in the laboratory mouse. By collecting and integrating different types of expression data, GXD provides information about expression profiles in different mouse strains and mutants. Participation in the Gene Ontology (GO) project classifies genes and gene products with regard to molecular functions, biological processes, and cellular components. Integration with other Mouse Genome Informatics (MGI) databases places the gene expression information in the context of mouse genetic, genomic and phenotypic information. The integration of these types of information enables valuable insights into the molecular biology that underlies development and disease. The utility of GXD has been improved by the daily addition of new data and through the implementation of new query and display features. These improvements make it easier for users to interrogate and visualize expression data in the context of their specific needs. GXD is accessible through the MGI website at http://www.informatics.jax.org/ or directly at http://www.informatics.jax.org/menus/expression_menu.shtml.

引用

页码：D568 / D571

页数：4

共 28 条

[1] The InterPro database, an integrated documentation resource for protein families, domains and functional sites [J].

Apweiler, R ;

Attwood, TK ;

Bairoch, A ;

Bateman, A ;

Birney, E ;

Biswas, M ;

Bucher, P ;

Cerutti, T ;

Corpet, F ;

Croning, MDR ;

Durbin, R ;

Falquet, L ;

Fleischmann, W ;

Gouzy, J ;

Hermjakob, H ;

Hulo, N ;

Jonassen, I ;

Kahn, D ;

Kanapin, A ;

Karavidopoulou, Y ;

Lopez, R ;

Marx, B ;

Mulder, NJ ;

Oinn, TM ;

Pagni, M ;

Servant, F ;

Sigrist, CJA ;

Zdobnov, EM .

NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :37-40

[2] Connecting sequence and biology in the laboratory mouse [J].

Baldarelli, RM ;

Hill, DP ;

Blake, JA ;

Adachi, J ;

Furuno, M ;

Bradt, D ;

Corbani, LE ;

Cousins, S ;

Frazer, KS ;

Qi, D ;

Yang, LL ;

Ramachandran, S ;

Reed, D ;

Zhu, YX ;

Kasukawa, T ;

Ringwald, M ;

King, BL ;

Maltais, LJ ;

McKenzie, LM ;

Schriml, LM ;

Maglott, D ;

Church, DM ;

Pruitt, K ;

Eppig, JT ;

Richardson, JE ;

Kadin, JA ;

Bult, CJ .

GENOME RESEARCH, 2003, 13 (6B) :1505-1519

[3] An internet-accessible database of mouse developmental anatomy based on a systematic nomenclature [J].

Bard, JBL ;

Kaufman, MH ;

Dubreuil, C ;

Brune, RM ;

Burger, A ;

Baldock, RA ;

Davidson, DR .

MECHANISMS OF DEVELOPMENT, 1998, 74 (1-2) :111-120

[4] Electronic tools to manage gene expression data [J].

Begley, DA ;

Ringwald, M .

TRENDS IN GENETICS, 2002, 18 (02) :108-110

[5]

Benson DA, 2003, NUCLEIC ACIDS RES, V31, P23, DOI 10.1093/nar/gkg057

[6] The Protein Data Bank [J].

Berman, HM ;

Westbrook, J ;

Feng, Z ;

Gilliland, G ;

Bhat, TN ;

Weissig, H ;

Shindyalov, IN ;

Bourne, PE .

NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242

[7] MGD: the Mouse Genome Database [J].

Blake, JA ;

Richardson, JE ;

Bult, RJ ;

Kadin, JA ;

Eppig, JT .

NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :193-195

[8] The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 [J].

Boeckmann, B ;

Bairoch, A ;

Apweiler, R ;

Blatter, MC ;

Estreicher, A ;

Gasteiger, E ;

Martin, MJ ;

Michoud, K ;

O'Donovan, C ;

Phan, I ;

Pilbout, S ;

Schneider, M .

NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :365-370

[9] The Mouse Genome Database (MGD): integrating biology with the genome [J].

Bult, CJ ;

Blake, JA ;

Richardson, JE ;

Kadin, JA ;

Eppig, JT .

NUCLEIC ACIDS RESEARCH, 2004, 32 :D476-D481

[10] The MouseAtlas Database:: a community resource for mouse development [J].

Davidson, D ;

Bard, J ;

Kaufman, M ;

Baldock, R .

TRENDS IN GENETICS, 2001, 17 (01) :49-51

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