A Low-Fat Diet Combined with Moderate-Intensity Aerobic Exercise is More Effective than a Low-Fat Diet or Aerobic Exercise Alone on Dyslipi-demia and Depression Status in Obese Patients: A Randomized Controlled Trial

被引：3

作者：

Abdelbasset, Walid Kamal ^{[1
,2
]}

Nambi, Gopal ^{[1
]}

Alsubaie, Saud F. ^{[1
]}

Elsayed, Shereen H. ^{[3
,4
]}

Eid, Marwa M. ^{[5
,6
]}

Soliman, Gaber S. ^{[4
,7
]}

Ibrahim, Ahmed A. ^{[8
]}

Abdelaziz, Mohamed A. ^{[9
,10
]}

机构：

[1] Prince Sattam Bin Abdulaziz Univ, Dept Hlth & Rehabil Sci, Coll Appl Med Sci, Alkharj, Saudi Arabia

[2] Cairo Univ, Dept Phys Therapy, Kasr Al Aini Hosp, Giza, Egypt

[3] Princess Nourah Bint Abdulrahman Univ, Dept Rehabil Sci, Fac Hlth & Rehabil, Riyadh, Saudi Arabia

[4] Cairo Univ, Dept Cardiovasc Resp Disorder & Geriatr, Fac Phys Therapy, Giza, Egypt

[5] Cairo Univ, Dept Phys Therapy Surg, Fac Phys Therapy, Giza, Egypt

[6] Taif Univ, Dept Phys Therapy, Coll Appl Med Sci, At Taif, Saudi Arabia

[7] Jouf Univ, Dept Phys Therapy & Hlth Rehabil, Coll Appl Med Sci, Sakaka, Saudi Arabia

[8] Hail Univ, Dept Phys Therapy, Coll Appl Med Sci, Hail, Saudi Arabia

[9] Prince Sattam Bin Abdulaziz Univ, Dept Basic Med Sci, Coll Med, Al Kharj, Saudi Arabia

[10] Al Azhar Univ, Dept Med Physiol, Fac Med, Cairo, Egypt

来源：

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS | 2021年 / 21卷 / 12期

关键词：

Obesity; low-fat diet; aerobic exercise; dyslipidemia; depression; lipid profile; SERUM-CHOLESTEROL; MAJOR DEPRESSION;

D O I：

10.2174/1871530321666210406161226

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background & Objective: Exercise and dietary interventions are used to control dyslipidemia and depression in obese individuals, whilst rare investigations have examined the concurrent effects of a low-fat diet and moderate-intensity aerobic exercise training (MIAET) on dyslipidemia and depression in obese patients. Hence, we assessed the potential influences of a low-fat diet combined with MIAET on blood lipids and depression in those individuals. Methods: Forty-two obese patients aged 30-50 years have been enrolled in this randomized controlled trial. They have been randomized equally into MIAET group (n=14, 60-70% of the maximum heart rate (Max HR), three sessions a week), a low-fat diet group (n=14, fat, 30% Kcal/day), and a low-fat diet plus MIAET (n=14) for 10 consecutive weeks. Body mass index (BMI), lipid profile, and Hamilton depression rating scale (HDRS) have been assessed on two occasions, pre and post- 10 weeks. Results: It was demonstrated that a low-fat diet group showed an improvement in total cholesterol (T-Ch), p=0.046, with no changes in triglycerides (TGs), p=0.343, low-density lipoproteins (LDLs), p=0.187, and high-density lipoproteins (HDLs), p=0.224; however, MIAET group showed an improvement in TGs, p=0.042, HDLs, p=0.038 with no changes in T-Ch, p=0.126, and LDLs, p=0.368. Regarding the low-fat diet plus MIAET group, significant improvements were identified in TGs, p=0.003, T-Ch, p<0.001, LDLs, p=0.004, and HDLs, p<0.001. For the depression status, all groups showed a significant improvement in HDRS, p<0.001, with a low-fat diet plus MIAET group showing greater advantages, p<0.05. Conclusion: The results of the current trial suggest an important implication for promoting improvement in blood lipids and a reduction in depression status in obese patients with dyslipidemia following 10-week of a concurrent low-fat diet and moderate-intensity aerobic exercise more than low-fat diet or MIAET alone.

引用

页码：2289 / 2295

页数：7

共 30 条

[1]

Abdelbasset WK, 2020, KARDIOLOGIYA, V60, P102, DOI 10.18087/cardio.2020.6.n938

[2] RETRACTED: Effect of Moderate-Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single-Blinded Randomised Controlled Trial (Retracted Article) [J].