Biphenylene-substituted ruthenocenylphosphine for Suzuki-Miyaura coupling of aryl chlorides

被引：58

作者：

Hoshi, Takashi ^{[1
]}

Nakazawa, Taichi ^{[2
]}

Saitoh, Ippei ^{[2
]}

Mori, Ayako ^{[1
]}

Suzuki, Toshio ^{[1
]}

Sakai, Jun-ichi ^{[1
]}

Hagiwara, Hisahiro ^{[2
]}

机构：

[1] Niigata Univ, Fac Engn, Niigata 9502181, Japan

[2] Niigata Univ, Grad Sch Sci & Technol, Nishi Ku, Niigata 9502181, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 10期

关键词：

D O I：

10.1021/ol800567q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

High activity in the palladium-catalyzed Suzuki-Miyaura reactions of aryl chlorides with arylboronic acids was furnished using biphenylene-substituted di-tert-butylruthenocenylphosphine (R-Phos) as a supporting ligand. Substrate combinations even for the construction of highly hindered tetra- ortho-substituted biaryls can be achieved in good to excellent yields with low catalyst loadings in short reaction times.

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页码：2063 / 2066

页数：4

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