Inhibitory activity of origanum essential oil against important fungus in veterinary

被引：18

作者：

Cleff, M. B. ^{[1
]}

Meinerz, A. R. ^{[2
]}

Faria, R. O. ^{[2
]}

Xavier, M. O. ^{[1
]}

Santin, R. ^{[2
]}

Nascente, P. S. ^{[2
]}

Rodrigues, M. R. ^{[3
]}

Meireles, M. C. A. ^{[1
]}

机构：

[1] Univ Fed Pelotas, Fac Vet, Pelotas, RS, Brazil

[2] FV UFRGS, Porto Alegre, RS, Brazil

[3] Univ Fed Pelotas, Inst Quim, Pelotas, RS, Brazil

来源：

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA | 2010年 / 62卷 / 05期

关键词：

fungal; essential oil; origanum; CARVACROL;

D O I：

10.1590/S0102-09352010000500040

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The in vitro activity of Origanum vulgare essential oil against fungal isolates was evaluated. A total of 27 clinical isolates were used, including: C. albicans, S. schenckii, M. pachydermatis, Aspergillus flavus, and A. fumigatus. Microdilution in broth technique (NCCLS M27-A2 and M-38) was used and susceptibility was expressed as Minimum Inhibitory Concentration (MIC). Essential oil was obtained by hydrodistillation in Clevenger and analyzed by gas chromatography, showing the presence of 4-terpineol, alpha-terpineol, 4-terpinene, thymol and carvacrol, as the main compounds. Origanum oil MIC for C. albicans varied from 125 to 500 mu L/mL; for S. schenckii, from 250 to 500 mu L/mL; for M. pachydermatis, from 15 to 30 mu L/mL; and for Aspergillus, from 30 to 60 mu L/mL. Isolates sensitivity showed to the origanum oil stimulates the accomplishment of new studies, including in vivo tests, contributing to the search of alternative treatments to mycosis.

引用

页码：1291 / 1294

页数：4

共 10 条

[1]

Carmo ES, 2008, BRAZ J MICROBIOL, V39, P362, DOI [10.1590/S1517-83822008000200030, 10.1590/S1517-838220080002000030]

[2]

Chami N., 2004, Braz J Infect Dis, V8, P217, DOI 10.1590/S1413-86702004000300005

[3]

Cleff MB, 2010, BRAZ J MICROBIOL, V41, P116, DOI 10.1590/S1517-838220100001000018

[4] Antifungal effect of various essential oils against Candida albicans.: Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris [J].