Lipid rafts and their roles in T-cell activation

被引:39
|
作者
Horejsí, V [1 ]
机构
[1] Acad Sci Czech Republ, Inst Mol Genet, CR-14220 Prague, Czech Republic
关键词
lipid rafts; T-cell; immunoreceptor signaling;
D O I
10.1016/j.micinf.2004.12.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and protein composition. They are involved in many aspects of cell biology, including T-cell activation and immunoreceptor signaling. This review discusses current controversies around lipid rafts and summarizes recent developments in the area. (c) 2005 Elsevier SAS. All rights reserved.
引用
收藏
页码:310 / 316
页数:7
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