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New Norcucurbitane Triterpenoids from Momordica charantia var. abbreviata
被引:1
作者:
Chen, Chiy-Rong
[1
]
Liao, Yun-Wen
[2
]
Kuo, Yueh-Hsiung
[3
,4
]
Hsu, Jue-Liang
[2
]
Chang, Chi-I
[2
]
机构:
[1] Natl Taitung Univ, Dept Life Sci, Taitung 95002, Taiwan
[2] Natl Pingtung Univ Sci & Technol, Dept Biol Sci & Technol, Pingtung 91201, Taiwan
[3] China Med Univ, Coll Pharm, Dept Chinese Pharmaceut Sci & Chinese Med Resourc, Taichung 40402, Taiwan
[4] Asia Univ, Dept Biotechnol, Taichung 41354, Taiwan
关键词:
Momordica charantia var. abbreviata;
Cucurbitaceae;
Fruit;
Triterpenoid;
Norcucurbitane;
CUCURBITANE-TYPE TRITERPENOIDS;
HYDROPEROXIDE-INDUCED HEPATOTOXICITY;
INDUCED INFLAMMATION;
EXTRACT;
CELLS;
FRUIT;
SER;
L;
ANTIOXIDANT;
COMPONENTS;
D O I:
暂无
中图分类号:
R914 [药物化学];
学科分类号:
100701 ;
摘要:
Two new 27-norcucurbitane triterpenoids, 5 beta,19-epoxy-3 beta-hydroxy-19(S)-methoxy-27-norcucurbita-6,23(E)-dien-25-one (1) and 3 beta-hydroxy-25-oxo-27-norcucurbita-6,23(E)-dien-5 beta,19-olide (2), together with one known cucurbitane triterpene, 5 beta,19-epoxycucurbita-6,23(E)-diene-3 beta,25-diol (3), were isolated from the fruits of Momordica charantia var. abbreviata. Their structures were elucidated by spectroscopic methods including EI-MS, H-1, C-13, and 2D NMR data and comparison with the data of known analogues.
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页码:1013 / 1016
页数:4
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