New Norcucurbitane Triterpenoids from Momordica charantia var. abbreviata

被引:1
作者
Chen, Chiy-Rong [1 ]
Liao, Yun-Wen [2 ]
Kuo, Yueh-Hsiung [3 ,4 ]
Hsu, Jue-Liang [2 ]
Chang, Chi-I [2 ]
机构
[1] Natl Taitung Univ, Dept Life Sci, Taitung 95002, Taiwan
[2] Natl Pingtung Univ Sci & Technol, Dept Biol Sci & Technol, Pingtung 91201, Taiwan
[3] China Med Univ, Coll Pharm, Dept Chinese Pharmaceut Sci & Chinese Med Resourc, Taichung 40402, Taiwan
[4] Asia Univ, Dept Biotechnol, Taichung 41354, Taiwan
关键词
Momordica charantia var. abbreviata; Cucurbitaceae; Fruit; Triterpenoid; Norcucurbitane; CUCURBITANE-TYPE TRITERPENOIDS; HYDROPEROXIDE-INDUCED HEPATOTOXICITY; INDUCED INFLAMMATION; EXTRACT; CELLS; FRUIT; SER; L; ANTIOXIDANT; COMPONENTS;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new 27-norcucurbitane triterpenoids, 5 beta,19-epoxy-3 beta-hydroxy-19(S)-methoxy-27-norcucurbita-6,23(E)-dien-25-one (1) and 3 beta-hydroxy-25-oxo-27-norcucurbita-6,23(E)-dien-5 beta,19-olide (2), together with one known cucurbitane triterpene, 5 beta,19-epoxycucurbita-6,23(E)-diene-3 beta,25-diol (3), were isolated from the fruits of Momordica charantia var. abbreviata. Their structures were elucidated by spectroscopic methods including EI-MS, H-1, C-13, and 2D NMR data and comparison with the data of known analogues.
引用
收藏
页码:1013 / 1016
页数:4
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