DAnTE: a statistical tool for quantitative analysis of -omics data

被引：356

作者：

Polpitiya, Ashoka D. ^{[1
]}

Qian, Wei-Jun ^{[1
]}

Jaitly, Navdeep ^{[1
]}

Petyuk, Vladislav A. ^{[1
]}

Adkins, Joshua N. ^{[1
]}

Camp, David G., II ^{[1
]}

Anderson, Gordon A. ^{[1
]}

Smith, Richard D. ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Richland, WA 99352 USA

来源：

BIOINFORMATICS | 2008年 / 24卷 / 13期

关键词：

D O I：

10.1093/bioinformatics/btn217

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly.

引用

页码：1556 / 1558

页数：3

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