Pericardial adipose tissue is an independent risk factor of coronary artery disease and is associated with risk factors of coronary artery disease

被引：12
作者：
Si, Yueqiao [1 ]
Cui, Zhixin [2 ]
Liu, Jingyi [1 ]
Ding, Zhenjiang [1 ]
Han, Chao [1 ]
Wang, Ruijuan [1 ]
Liu, Tong [1 ]
Sun, Lixian [1 ]
机构：
[1] Chengde Med Univ, Affiliated Hosp, Dept Cardiol, 36 Nanyingzi St, Chengde 067000, Hebei, Peoples R China
[2] Chengde Med Univ, Affiliated Hosp, Dept Radiol, Chengde, Hebei, Peoples R China
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2020年 / 48卷 / 06期
关键词：
Pericardial adipose tissue; coronary artery disease; computed tomographic angiography; fat volume; pulse pressure; body mass index; cholesterol; ATRIAL-FIBRILLATION; COMPUTED-TOMOGRAPHY; INTRATHORACIC FAT; EPICARDIAL FAT; PULSE PRESSURE; VOLUME; CT; ATHEROSCLEROSIS; CALCIFICATION; SEVERITY;
D O I：
10.1177/0300060520926737
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective Pericardial adipose tissue volume (PATV) is related to the mechanism of coronary artery disease (CAD), but its association with CAD risk factors is not clear. This study aimed to investigate the relationships between PATV and its associated factors. Methods A total of 682 inpatients were consecutively enrolled in this study. Patients were divided into the high PATV group (PATV >= 174.5 cm(3); n = 506) and low PATV group (PATV < 174.5 cm(3); n = 176). Multiple linear regression analysis was conducted to evaluate the related factors of PATV. Multivariable logistic regression was used to analyze the risk factors of CAD. Results Left ventricular fat volume, right ventricular fat volume, body mass index, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were significant and independent risk factors of enlargement of PATV. Increased PATV was identified as an independent risk factor of CAD, and increased pulse pressure was also independently and positively correlated with CAD. Conclusions PATV is significantly correlated with the classic risk factors of CAD. Pulse pressure is also correlated with PATV. PATV is an independent risk factor of CAD, and pericardial adipose tissue may alternatively be used in non-invasive diagnostic examination of CAD.
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页数：11
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