Innate lymphoid cells wield a double-edged sword

被引：27

作者：

Wills-Karp, Marsha ^{[1
]}

Finkelman, Fred D. ^{[1
,2
]}

机构：

[1] Cincinnati Childrens Hosp, Med Ctr, Div Immunobiol, Cincinnati, OH USA

[2] Univ Cincinnati, Coll Med, Dept Med, Cincinnati Vet Affairs Med Ctr, Cincinnati, OH USA

来源：

NATURE IMMUNOLOGY | 2011年 / 12卷 / 11期

关键词：

EPIDERMAL-GROWTH-FACTOR; TYPE-2; IMMUNITY; CYTOKINES; RECEPTOR; ASTHMA; AIRWAY; IL-33; IL-13;

D O I：

10.1038/ni.2142

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Type 2 cytokine-producing innate lymphoid cells are present in human and mouse lungs, where they contribute to both type 2 immune responses and tissue repair.

引用

页码：1025 / 1027

页数：3

共 14 条

[1] Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity [J].

Chang, Ya-Jen ;

Kim, Hye Young ;

Albacker, Lee A. ;

Baumgarth, Nicole ;

McKenzie, Andrew N. J. ;

Smith, Dirk E. ;

DeKruyff, Rosemarie H. ;

Umetsu, Dale T. .

NATURE IMMUNOLOGY, 2011, 12 (07) :631-U186

[2] Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack [J].

Enomoto, Yukinori ;

Orihara, Kanami ;

Takamasu, Tetsuya ;

Matsuda, Akio ;

Gon, Yasuhiro ;

Saito, Hirohisa ;

Ra, Chisei ;

Okayama, Yoshimichi .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 124 (05) :913-920

[3] IL-25 induces IL-4 IL-5, and IL-13 and Th2-associated pathologies in vivo [J].

Fort, MM ;

Cheung, J ;

Yen, D ;

Li, J ;

Zurawski, SM ;

Lo, S ;

Menon, S ;

Clifford, T ;

Hunte, B ;

Lesley, R ;

Muchamuel, T ;

Hurst, SD ;

Zurawski, G ;

Leach, MW ;

Gorman, DM ;

Rennick, DM .

IMMUNITY, 2001, 15 (06) :985-995

[4] Role of IL-33 in inflammation and disease [J].

Miller, Ashley M. .

JOURNAL OF INFLAMMATION-LONDON, 2011, 8

[5] Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161 [J].

Mjosberg, Jenny M. ;

Trifari, Sara ;

Crellin, Natasha K. ;

Peters, Charlotte P. ;

van Drunen, Cornelis M. ;

Piet, Berber ;

Fokkens, Wytske J. ;

Cupedo, Tom ;

Spits, Hergen .

NATURE IMMUNOLOGY, 2011, 12 (11) :1055-U56

[6]

Monticelli LA, 2011, NAT IMMUNOL, V12, P1045, DOI [10.1038/ni.2131, 10.1031/ni.2131]

[7] Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells [J].

Moro, Kazuyo ;

Yamada, Taketo ;

Tanabe, Masanobu ;

Takeuchi, Tsutomu ;

Ikawa, Tomokatsu ;

Kawamoto, Hiroshi ;

Furusawa, Jun-ichi ;

Ohtani, Masashi ;

Fujii, Hideki ;

Koyasu, Shigeo .

NATURE, 2010, 463 (7280) :540-U160

[8] Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity [J].

Neill, Daniel R. ;

Wong, See Heng ;

Bellosi, Agustin ;

Flynn, Robin J. ;

Daly, Maria ;

Langford, Theresa K. A. ;

Bucks, Christine ;

Kane, Colleen M. ;

Fallon, Padraic G. ;

Pannell, Richard ;

Jolin, Helen E. ;

McKenzie, Andrew N. J. .

NATURE, 2010, 464 (7293) :1367-U9

[9] Systemically dispersed innate IL-13-expressing cells in type 2 immunity [J].

Price, April E. ;

Liang, Hong-Erh ;

Sullivan, Brandon M. ;

Reinhardt, R. Lee ;

Eisley, Chris J. ;

Erle, David J. ;

Locksley, Richard M. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (25) :11489-11494

[10] Viral respiratory tract infections and asthma: The course ahead [J].

Rosenthal, Louis A. ;

Avila, Pedro C. ;

Heymann, Peter W. ;

Martin, Richard J. ;

Miller, E. Kathryn ;

Papadopoulos, Nikolaos G. ;

Peebles, R. Stokes, Jr. ;

Gern, James E. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 125 (06) :1212-1217

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