Interfacial pockets, structurally conserved residues, and energetic hot spots in protein-protein interactions

被引:0
|
作者
Li, X
Keskin, O
Ma, BY
Nussinov, R
Liang, J
机构
[1] Univ Illinois, Dept Bioengn, Chicago, IL USA
[2] Bogazici Univ, Dept Chem Engn, Istanbul, Turkey
[3] Bogazici Univ, Ctr Polymer Res, Istanbul, Turkey
[4] NCI, FCRDC, Lab Expt & Computat Biol, Frederick, MD 21701 USA
[5] Tel Aviv Univ, Sackler Inst Mol Med, IL-69978 Tel Aviv, Israel
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:301A / 301A
页数:1
相关论文
共 50 条
  • [21] Interfacial residues in protein-protein complexes are in the eyes of the beholder
    Parvathy, Jayadevan
    Yazhini, Arangasamy
    Srinivasan, Narayanaswamy
    Sowdhamini, Ramanathan
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2024, 92 (04) : 509 - 528
  • [22] Trp/Met/Phe hot spots in protein-protein interactions: Potential targets in drug design
    Ma, Buyong
    Nussinov, Ruth
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2007, 7 (10) : 999 - 1005
  • [23] Prediction of mechanically hot spots in protein-protein interactions using perturbation response scanning method
    Abdizadeh, Haleh
    Atilgan, Alirana
    Atilgan, Canan
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [24] Hot spots in protein-protein interfaces: Towards drug discovery
    Cukuroglu, Engin
    Engin, H. Billur
    Gursoy, Attila
    Keskin, Ozlem
    PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2014, 116 (2-3): : 165 - 173
  • [25] Structural conservation of druggable hot spots in protein-protein interfaces
    Kozakov, Dima
    Hall, David R.
    Chuang, Gwo-Yu
    Cencic, Regina
    Brenke, Ryan
    Grove, Laurie E.
    Beglov, Dmitri
    Pelletier, Jerry
    Whitty, Adrian
    Vajda, Sandor
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (33) : 13528 - 13533
  • [26] Identification of hot spot residues at protein-protein interface
    Li, Lei
    Zhao, Bing
    Cui, Zhanhua
    Gan, Jacob
    Sakharkar, Meena Kishore
    Kangueane, Pandjassarame
    BIOINFORMATION, 2006, 1 (04) : 121 - +
  • [27] Correlating Protein Hot Spot Surface Analysis Using ProBiS with Simulated Free Energies of Protein-Protein Interfacial Residues
    Carl, Nejc
    Hodoscek, Milan
    Vehar, Blaz
    Konc, Janez
    Brooks, Bernard R.
    Janezic, Dusanka
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2012, 52 (10) : 2541 - 2549
  • [28] Prediction of protein-protein binding hot spots: A combination of classifiers approach
    Higa, Roberto Hiroshi
    Tozzi, Clesio Luis
    ADVANCES IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, PROCEEDINGS, 2008, 5167 : 165 - +
  • [29] PPI-HotspotDB: Database of Protein-Protein Interaction Hot Spots
    Chen, Yao Chi
    Chen, Yu-Hsien
    Wright, Jon D.
    Lim, Carmay
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 62 (04) : 1052 - 1060
  • [30] Restricted mobility of conserved residues in protein-protein interfaces in molecular simulations
    Yogurtcu, Osman N.
    Erdemli, S. Bora
    Nussinov, Ruth
    Turkay, Metin
    Keskin, Ozlem
    BIOPHYSICAL JOURNAL, 2008, 94 (09) : 3475 - 3485