Dim light at night increases body mass of female mice

被引:38
作者
Aubrecht, Taryn G. [1 ]
Jenkins, Richelle [1 ]
Nelson, Randy J. [1 ]
机构
[1] Ohio State Univ, Wexner Med Ctr, Dept Neurosci, Neurosci Res Inst, Columbus, OH 43210 USA
关键词
Body mass regulation; circadian disruption; light pollution; light at night; METABOLIC SYNDROME; BREAST-CANCER; DISRUPTION; OBESITY; RHYTHM; INDEX; TIME; RISK;
D O I
10.3109/07420528.2014.986682
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
During the past century, the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16 h light at similar to 150 lux/8 h dark at similar to 0 lux) cycle or to light/dim light at night (dLAN; 16 h light at similar to 150 lux/8 h dim light at similar to 5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism.
引用
收藏
页码:557 / 560
页数:4
相关论文
共 18 条
[1]   THE EFFECT OF DIFFERENT LIGHT INTENSITIES ON PINEAL MELATONIN CONTENT [J].
BRAINARD, GC ;
RICHARDSON, BA ;
PETTERBORG, LJ ;
REITER, RJ .
BRAIN RESEARCH, 1982, 233 (01) :75-81
[2]   Combination of Light and Melatonin Time Cues for Phase Advancing the Human Circadian Clock [J].
Burke, Tina M. ;
Markwald, Rachel R. ;
Chinoy, Evan D. ;
Snider, Jesse A. ;
Bessman, Sara C. ;
Jung, Christopher M. ;
Wright, Kenneth P., Jr. .
SLEEP, 2013, 36 (11) :1617-1624
[3]   Prevalence and Trends in Obesity Among US Adults, 1999-2008 [J].
Flegal, Katherine M. ;
Carroll, Margaret D. ;
Ogden, Cynthia L. ;
Curtin, Lester R. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (03) :235-241
[4]   Dark Nights Reverse Metabolic Disruption Caused by Dim Light at Night [J].
Fonken, L. K. ;
Weil, Z. M. ;
Nelson, R. J. .
OBESITY, 2013, 21 (06) :1159-1164
[5]   Dim Light at Night Disrupts Molecular Circadian Rhythms and Increases Body Weight [J].
Fonken, Laura K. ;
Aubrecht, Taryn G. ;
Melendez-Fernandez, O. Hecmarie ;
Weil, Zachary M. ;
Nelson, Randy J. .
JOURNAL OF BIOLOGICAL RHYTHMS, 2013, 28 (04) :262-271
[6]  
Fonken Laura K, 2011, F1000 Med Rep, V3, P18, DOI 10.3410/M3-18
[7]   Light at night increases body mass by shifting the time of food intake [J].
Fonken, Laura K. ;
Workman, Joanna L. ;
Walton, James C. ;
Weil, Zachary M. ;
Morris, John S. ;
Haim, Abraham ;
Nelson, Randy J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (43) :18664-18669
[8]   A clockwork web: Circadian timing in brain and periphery, in health and disease [J].
Hastings, MH ;
Reddy, AB ;
Maywood, ES .
NATURE REVIEWS NEUROSCIENCE, 2003, 4 (08) :649-661
[9]   Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women [J].
Key, TJ ;
Appleby, PN ;
Reeves, GK ;
Roddam, A ;
Dorgan, JF ;
Longcope, C ;
Stanczyk, FZ ;
Stephenson, HE ;
Falk, RT ;
Miller, R ;
Schatzkin, A ;
Allen, DS ;
Fentiman, IS ;
Key, TJ ;
Wang, DY ;
Dowsett, M ;
Thomas, HV ;
Hankinson, SE ;
Toniolo, P ;
Koenig, K ;
Shore, RE ;
Zeleniuch-Jacquotte, A ;
Berrino, F ;
Muti, P ;
Micheli, A ;
Krogh, V ;
Sieri, S ;
Pala, V ;
Venturelli, E ;
Secreto, G ;
Barrett-Connor, E ;
Laughlin, GA ;
Kabuto, M ;
Akiba, S ;
Stevens, RG ;
Neriishi, K ;
Land, CE ;
Cauley, JA ;
Kuller, LH ;
Cummings, SR ;
Helzlsouer, KJ ;
Alberg, AJ ;
Bush, TL ;
Comstock, GW ;
Gordon, GB ;
Miller, SR .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (16) :1218-1226
[10]   High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light [J].
Lockley, SW ;
Brainard, GC ;
Czeisler, CA .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (09) :4502-4505