A Meta-Analysis of Neuropsychological Functioning in Patients with Early Onset Schizophrenia and Pediatric Bipolar Disorder

被引：60

作者：

Nieto, Rebeca Garcia ^{[1
]}

Castellanos, F. Xavier ^{[1
,2
,3
]}

机构：

[1] New York Univ Langone Med Ctr, Ctr Child Study, New York, NY USA

[2] New York Univ Langone Med Ctr, Phyllis Green & Randolph Cwen Inst Pediat Neurosci, New York, NY USA

[3] Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA

来源：

JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY | 2011年 / 40卷 / 02期

关键词：

COMPARATIVE PROFILE ANALYSIS; 1ST EPISODE PSYCHOSIS; COGNITIVE DEFICITS; 1ST-EPISODE SCHIZOPHRENIA; NEUROCOGNITIVE FUNCTION; ADOLESCENTS; PERFORMANCE; IMPAIRMENT; CHILDHOOD; MEMORY;

D O I：

10.1080/15374416.2011.546049

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Despite the nosological distinction between bipolar disorder and schizophrenia, there is increasing evidence that these conditions share phenomenological characteristics. To examine the similarities in their patterns of cognitive impairment, we conducted a meta-analysis from 12 studies of Early Onset Schizophrenia (EOS) and 12 studies of Pediatric Bipolar Disorder (PBD). We found that individuals with PBD suffer from cognitive deficits (e.g., verbal learning and memory, processing speed, or executive control) that are milder but similar in nature to those of patients with EOS. Qualitative similarities between the neuropsychological profiles produced by these groups of patients might represent a ocontinuum of psychosiso or reflect some degree of genetic biological overlap.

引用

页码：266 / 280

页数：15

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