Report of a consensus meeting on focal low dose rate brachytherapy for prostate cancer

被引：78

作者：

Langley, Stephen ^{[1
]}

Ahmed, Hashim U. ^{[2
]}

Al-Qaisieh, Bashar ^{[3
]}

Bostwick, David

Dickinson, Louise ^{[2
]}

Gomez Veiga, Francisco ^{[4
]}

Grimm, Peter ^{[5
]}

Machtens, Stefan ^{[6
]}

Guedea, Ferran ^{[7
]}

Emberton, Mark ^{[2
]}

机构：

[1] Royal Surrey Cty Hosp NHS Fdn Trust, Dept Urol, Guildford GU2 7XX, Surrey, England

[2] UCL, Div Surg & Intervent Sci, London WC1E 6BT, England

[3] St Jamess Inst Oncol, Dept Med Phys, Leeds, W Yorkshire, England

[4] Complejo Hosp Univ, Dept Urol, La Coruna, Spain

[5] Prostate Canc Treatment Ctr Seattle, Seattle, WA USA

[6] Marien Krankenhaus, Dept Urol, Bergisch Gladbach, Germany

[7] Catalan Inst Oncol, Dept Radiat Oncol, Barcelona, Spain

来源：

BJU INTERNATIONAL | 2012年 / 109卷

关键词：

prostate cancer; brachytherapy; focal therapy; patient selection; outcome; INTENSITY FOCUSED ULTRASOUND; RADICAL PROSTATECTOMY; INDEX LESION; BIOPSY; THERAPY; TUMOR; IMPACT; CS-131; ULTRASONOGRAPHY; RECOMMENDATIONS;

D O I：

10.1111/j.1464-410X.2011.10825.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Low dose rate prostate brachytherapy is an effective treatment for localized prostate cancer. Recently, it has been considered for use in a focused manner whereby treatment is targeted only to areas of prostate cancer. The objective of focal brachytherapy is to provide effective cancer control for low-risk disease but with reduced genitourinary and rectal side-effects in a cost-effective way. We report on the outputs of a consensus meeting of international experts in brachytherapy and focal therapy convened to consider the feasibility and potential development of focal brachytherapy. A number of factors were considered for focal brachytherapy including optimal patient selection, disease characterization and localization, treatment protocols and outcome measures. The consensus meeting also addressed the design of a clinical trial that would assess the oncological outcomes and side-effect profiles resulting from focal brachytherapy.

引用

页码：7 / 16

页数：10

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