Management of Proteinuria in Dogs and Cats with Chronic Kidney Disease

被引：44
作者：
Vaden, Shelly L. [1 ]
Elliott, Jonathan [2 ]
机构：
[1] North Carolina State Univ, Coll Vet Med, Dept Clin Sci, 1052 William Moore Dr, Raleigh, NC 27607 USA
[2] Univ London, Royal Vet Coll, Dept Comparat Biomed Sci, Royal Coll St, London NW1 0TU, England
来源：
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2016年 / 46卷 / 06期
关键词：
Urine protein:creatinine ratio; Proteinuria; Hypertension; Angiotensin; Aldosterone; Glomerular; Chronic kidney disease; ANGIOTENSIN-CONVERTING ENZYME; GLOMERULAR-DISEASE; CONSENSUS RECOMMENDATIONS; SYSTEMIC HYPERTENSION; RECEPTOR BLOCKERS; IMMUNOSUPPRESSIVE TREATMENT; ALDOSTERONE SYSTEM; BENAZEPRIL; ENALAPRIL; TELMISARTAN;
D O I：
10.1016/j.cvsm.2016.06.009
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Proteinuria is a negative prognostic indicator for dogs and cats with chronic kidney disease. A normal dog or cat should excrete very little protein and have a urine protein:creatinine ratio that is less than 0.4, or less than 0.2, respectively; persistent proteinuria above this magnitude warrants attention. Administration of angiotensin converting enzyme inhibitors and/or angiotensin receptor blockers, blood pressure control and nutritional modification are considered a standard of care for renal proteinuria. Renal biopsy and administration of immunosuppressive agents should be considered in animals with glomerular proteinuria that have not responded to standard therapy. Targeted patient monitoring is essential when instituting management of proteinuria.
引用
收藏
页码：1115 / +
页数：17
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