The 2011 E. B. Hershberg Award for Important Discoveries in Medicinally Active Substances: (1S,3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a GABA Aminotransferase Inactivator and New Treatment for Drug Addiction and Infantile Spasms

被引：34
作者：
Silverman, Richard B. [1 ,2 ]
机构：
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Dept Mol Biosci, Chem Life Proc Inst, Ctr Mol Innovat & Drug Discovery, Evanston, IL 60208 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2012年 / 55卷 / 02期
基金：
美国国家卫生研究院;
关键词：
GAMMA-AMINOBUTYRIC-ACID; CONDITIONED PLACE PREFERENCE; VINYL-GABA; 4-AMINOBUTYRATE AMINOTRANSFERASE; ALANINE AMINOTRANSFERASE; GLUTAMATE-DECARBOXYLASE; TRIGGERED REINSTATEMENT; TRANSAMINASE INHIBITOR; RESTRICTED ANALOG; SENILE-DEMENTIA;
D O I：
10.1021/jm201650r
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：567 / 575
页数：9
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