Hybrids of RNA and arabinonucleic acids (ANA and 2′F-ANA) are substrates of ribonuclease h

被引：183
作者：
Damha, MJ
Wilds, CJ
Noronha, A
Brukner, I
Borkow, G
Arion, D
Parniak, MA
机构：
[1] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada
[2] McGill Univ, McGill AIDS Ctr, Montreal, PQ H3T 1E2, Canada
[3] McGill Univ, Fac Med, Montreal, PQ H3T 1E2, Canada
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1998年 / 120卷 / 49期
关键词：
D O I：
10.1021/ja982325+
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：12976 / 12977
页数：2
相关论文
共 22 条
[1]  
ALBERTS B, 1989, MOL BIOL CELL, P304
[2]  
BRACH AD, 1998, TIBS, V23, P45
[3]   Progress in antisense oligonucleotide therapeutic [J].
Crooke, ST ;
Bennett, CF .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1996, 36 :107-129
[4]   ANTISENSE L/D-OLIGODEOXYNUCLEOTIDE CHIMERAS - NUCLEASE STABILITY, BASE-PAIRING PROPERTIES, AND ACTIVITY AT DIRECTING RIBONUCLEASE-H [J].
DAMHA, MJ ;
GIANNARIS, PA ;
MARFEY, P .
BIOCHEMISTRY, 1994, 33 (25) :7877-7885
[5]   SOLUTION AND SOLID-PHASE CHEMICAL SYNTHESIS OF ARABINONUCLEOTIDES [J].
DAMHA, MJ ;
USMAN, N ;
OGILVIE, KK .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1989, 67 (05) :831-839
[6]   Modulation of RNase H activity by modified DNA probes: Major groove vs minor groove effects [J].
Daniher, AT ;
Xie, J ;
Mathur, S ;
Bashkin, JK .
BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (06) :1037-1042
[7]   MOLECULAR-STRUCTURE OF A DNA DECAMER CONTAINING AN ANTICANCER NUCLEOSIDE ARABINOSYLCYTOSINE - CONFORMATIONAL PERTURBATION BY ARABINOSYLCYTOSINE IN B-DNA [J].
GAO, YG ;
VANDERMAREL, GA ;
VANBOOM, JH ;
WANG, AHJ .
BIOCHEMISTRY, 1991, 30 (41) :9922-9931
[8]   The effect of two antipodal fluorine-induced sugar puckers on the conformation and stability of the Dickerson-Drew dodecamer duplex [d(CGCGAATTCGCG)]2 [J].
Ikeda, H ;
Fernandez, R ;
Wilk, A ;
Barchi, JJ ;
Huang, XL ;
Marquez, VE .
NUCLEIC ACIDS RESEARCH, 1998, 26 (09) :2237-2244
[9]   SYNTHESIS AND SOME PROPERTIES OF MODIFIED OLIGONUCLEOTIDES .2. OLIGONUCLEOTIDES CONTAINING 2'-DEOXY-2'-FLUORO-BETA-D-ARABINOFURANOSYL PYRIMIDINE NUCLEOSIDES [J].
KOIS, P ;
TOCIK, Z ;
SPASSOVA, M ;
REN, WY ;
ROSENBERG, I ;
SOLER, JF ;
WATANABE, KA .
NUCLEOSIDES & NUCLEOTIDES, 1993, 12 (10) :1093-1109
[10]   Binding affinity and specificity of Escherichia coli RNase H1: Impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids [J].
Lima, WF ;
Crooke, ST .
BIOCHEMISTRY, 1997, 36 (02) :390-398
123