Caveolin-1 - a protein implicated in cellular cholesterol homeostasis

被引：0
|
作者：
Robenek, MJ [1 ]
Plenz, G [1 ]
Troyer, D [1 ]
机构：
[1] Univ Munster, Inst Arterioskleroseforsch, D-4400 Munster, Germany
来源：
Cardio-Visions 2004: JUNGE EXZELLENZE IN DER KARDIOVASKULAREN FORSCHUNG | 2005年
关键词：
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We studied the distribution of caveolin-1 in cell membranes and how caveolin-1 accesses lipid droplets from the endoplasmic reticulum (ER) in vascular smooth muscle cells (SMC) using freeze-fracture immunocytochemistry. We found caveolin-1 in the cytoplasmic leaflet of the plasma membrane, but surprisingly exclusively in the endoplasmic leaflet of all intracellular membranes. Furthermore, we localized caveolin-1 in notable amounts both on the surface and within the cores of lipid droplets.
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页码：69 / 70
页数：2
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