Correlation of Visual Quality of Life With Clinical and Visual Status in Friedreich Ataxia

被引：3

作者：

Afsharian, Parisa ^{[1
]}

Nolan-Kenney, Rachel ^{[2
,3
,4
]}

Lynch, Abigail E. ^{[1
]}

Balcer, Laura J. ^{[2
,3
,4
]}

Lynch, David R. ^{[1
]}

机构：

[1] Childrens Hosp Philadelphia, Div Neurol, 502 Abramson Res Ctr,3615 Civ Ctr Blvd, Philadelphia, PA 19104 USA

[2] NYU Sch Med, Sackler Inst Grad Biomed Sci, Dept Neurol, New York, NY USA

[3] NYU Sch Med, Sackler Inst Grad Biomed Sci, Dept Populat Hlth, New York, NY USA

[4] NYU Sch Med, Sackler Inst Grad Biomed Sci, Dept Ophthalmol, New York, NY USA

来源：

JOURNAL OF NEURO-OPHTHALMOLOGY | 2020年 / 40卷 / 02期

关键词：

INVOLVEMENT; PROGRESSION; FEATURES; ACUITY; SYSTEM;

D O I：

10.1097/WNO.0000000000000878

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: The primary objective was to determine the association of patient-reported vision-specific quality of life to disease status and visual function in patients with Friedreich's ataxia (FRDA). Methods: Patients with FRDA were assessed with the 25-Item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) along with measures of disease status (ataxia stage) and visual function (low- and high-contrast letter acuity scores). The relations of NEI-VFQ-25 scores to those for disease status and visual function were examined. Results: Scores for the NEI-VFQ-25 were lower in patients with FRDA (n = 99) compared with published disease-free controls, particularly reduced in a subgroup of FRDA patients with features of early onset, older age, and abnormal visual function. Conclusions: The NEI-VFQ-25 captures the subjective component of visual function in patients with FRDA.

引用

页码：213 / 217

页数：5

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