A total synthesis of (±)-α-cyclopiazonic acid using a cationic cascade as a key step

被引：30

作者：

Griffiths-Jones , Charlotte M. ^{[1
]}

Knight, David W. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Chem, Main Coll, Cardiff CF10 3AT, S Glam, Wales

来源：

TETRAHEDRON | 2011年 / 67卷 / 44期

基金：

英国工程与自然科学研究理事会;

关键词：

alpha-Cyclopiazonic acid; Synthesis; Carbenium ion; Cascade; Indole alkaloid; ALPHA-CYCLOPIAZONIC ACID; PENICILLIUM-CYCLOPIUM; STEREOSELECTIVE-SYNTHESIS; N-BOC; BIOSYNTHESIS; ROUTE; OXIDOCYCLASE; NITROACETATE; DERIVATIVES; MYCOTOXINS;

D O I：

10.1016/j.tet.2011.08.094

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The indole alkaloid alpha-cyclopiazonic acid 1 has been synthesised by a route, which features at its core an acid-catalysed cationic cascade cyclisation terminated by a sulfonamide group. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：8515 / 8528

页数：14

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