Electrical conductance measurement of HgII-mediated DNA duplex in buffered aqueous solution

被引：2
作者：
Yamada, Ryo [1 ]
Nomura, Issei [1 ]
Yamaguchi, Yuki [1 ]
Matsuda, Yosuke [2 ]
Hattori, Yoshikazu [2 ]
Tada, Hirokazu [1 ]
Ono, Akira [3 ]
Tanaka, Yoshiyuki [2 ]
机构：
[1] Osaka Univ, Grad Sch Engn Sci, Toyonaka, Osaka 5608531, Japan
[2] Tokushima Bunri Univ, Fac Pharmaceut Sci, 180 Nishihama Hoji, Yamashiro, Tokushima 7708514, Japan
[3] Kanagawa Univ, Dept Mat & Life Chem, Yokohama, Kanagawa, Japan
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2020年 / 39卷 / 08期
基金：
日本学术振兴会;
关键词：
Metallo-DNA; single-molecule conductance; scanning tunneling microscopy; break junction; SINGLE-MOLECULE CONDUCTANCE;
D O I：
10.1080/15257770.2020.1755044
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Electrical properties of metal-mediated DNA duplexes (metallo-DNA) have been of particular interest because of their potential applications in DNA-based nanoelectronics. We prepared Hg-II-mediated DNA duplex with NH2 anchors and measured the electrical conductance of single-molecule metallo-DNA via scanning tunneling microscopy-based break junction method in the buffered solution. Three conductance values were observed that may correspond to different conformations of the metallo-DNA molecule bridged over metallic electrodes.
引用
收藏
页码：1083 / 1087
页数：5
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