Optical Coherence Tomography for the Diagnosis and Evaluation of Human Otitis Media

被引：40

作者：

Cho, Nam Hyun ^{[1
]}

Lee, Sang Heun ^{[2
]}

Jung, Woonggyu ^{[3
]}

Jang, Jeong Hun ^{[4
]}

Kim, Jeehyun ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Sch Elect Engn, Daegu 700842, South Korea

[2] Daegu Vet Hosp, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea

[3] Ulsan Natl Inst Sci & Technol, Sch Nanobiosci & Chem Engn, Ulsan, South Korea

[4] Kyungpook Natl Univ, Coll Med, Dept Otorhinolaryngol, Daegu 700842, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2015年 / 30卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Tomography; Optical Coherence; Tympanic Membrane; Otitis Media; Ear; Middle; Clinical Study; HUMAN TYMPANIC MEMBRANE; MIDDLE-EAR; IN-VIVO; RAT COCHLEA; SD-OCT; INTERFEROMETRY; LANGUAGE; BIOFILM; SURGERY; SPEECH;

D O I：

10.3346/jkms.2015.30.3.328

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the application of optical coherence tomography (OCT) to the diagnosis and evaluation of otitis media (OM). Whereas conventional diagnostic modalities for OM, including standard and pneumatic otoscopy, are limited to visualizing the surface of the tympanic membrane (TM), OCT effectively reveals the depth-resolved microstructure below the TM with very high spatial resolution, with the potential advantage of its use for diagnosing different types of OM. We examined the use of 840-nm spectral domain-OCT (SD-OCT) clinically, using normal ears and ears with the adhesive and effusion types of OM. Specific features were identified in two-dimensional OCT images of abnormal TMs, compared to images of healthy TMs. Analysis of the A-scan (axial depth scan) identified unique patterns of constituents within the effusions. The OCT images could not only be used to construct a database for the diagnosis and classification of OM but OCT might also represent an upgrade over current otoscopy techniques.

引用

页码：328 / 335

页数：8

共 27 条

[1]

Boppart SA, 2004, MINERVA BIOTECNOL, V16, P211

[2]

Bouma B. E., 2002, Handbook of Optical Coherence Tomography, Patent No. 26406747

[3] Simultaneous 3D imaging of sound-induced motions of the tympanic membrane and middle ear ossicles [J].