Splenic Peliosis in a patient with aplastic anemia during danazol therapy

被引：3

作者：

Arai, Shunya ^{[1
]}

Asai, Takashi ^{[1
]}

Uozaki, Hiroshi ^{[2
]}

Hangaishi, Akira ^{[1
]}

Kanda, Yoshinobu ^{[1
]}

Motokura, Toru ^{[1
]}

Chiba, Shigeru ^{[1
]}

Kurokawa, Mineo ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Hematol & Oncol, Bunkyo Ku, Tokyo 1138655, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Pathol, Tokyo 1138655, Japan

来源：

INTERNATIONAL JOURNAL OF HEMATOLOGY | 2007年 / 86卷 / 04期

关键词：

spleen; peliosis; danazol; anabolic steroid; aplastic anemia;

D O I：

10.1532/IJH97.07078

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We experienced a case of danazol-induced splenic peliosis. A 42-year-old woman had taken danazol for refractory aplastic anemia for 2 years. Her anemia gradually became aggravated, and the patient complained of intermittent left upper-abdominal pain. Because computed tomography scanning showed multiple blood-filled cavities in the enlarged spleen without intraperitoneal hemorrhage, a splenectomy was emergently performed. This report is the first of a case of splenic peliosis developing during danazol therapy for aplastic anemia. The possible association between the administration of anabolic steroids or danazol and the development of peliosis is discussed.

引用

页码：329 / 332

页数：4

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