Uveitis in children

被引:25
作者
Angeles-Han, Sheila T. [1 ]
Rabinovich, Consuelo Egla [2 ]
机构
[1] Emory Univ, Sch Med, Atlanta, GA USA
[2] Duke Univ, Durham, NC USA
关键词
juvenile idiopathic arthritis; uveitis; risk factors; biological treatment; JUVENILE IDIOPATHIC ARTHRITIS; RHEUMATOID-ARTHRITIS; RISK-FACTORS; CHILDHOOD ARTHRITIS; PEDIATRIC UVEITIS; OUTCOME MEASURES; CLINICAL-TRIALS; VISUAL-ACUITY; PLASMA-CELLS; IRIDOCYCLITIS;
D O I
10.1097/BOR.0000000000000316
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review The review provides updates on novel risk markers for the development of pediatric inflammatory uveitis and a severe disease course, on treatment of refractory disease, and on the measurement of visual outcomes. Recent findings There are several new genetic markers, biomarkers, and clinical factors that may influence a child's uveitis disease course. It is important to identify children at risk for poor visual outcomes and who are refractory to traditional therapy. Racial disparities have recently been reported. We describe agents of potential benefit. In addition, we discuss the importance of patient reported outcomes in this population. Summary Uveitis can lead to vision-threatening complications. Timely and aggressive treatment of children identified to be at risk for a severe uveitis course may lead to improved outcomes.
引用
收藏
页码:544 / 549
页数:6
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